研究动态
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纤维化的放射学。第一部分:胸腔器官。

Radiology of fibrosis. Part I: Thoracic organs.

发表日期:2024 Jul 02
作者: Sofia Maria Tarchi, Mary Salvatore, Philip Lichtenstein, Thillai Sekar, Kathleen Capaccione, Lyndon Luk, Hiram Shaish, Jasnit Makkar, Elise Desperito, Jay Leb, Benjamin Navot, Jonathan Goldstein, Sherelle Laifer, Volkan Beylergil, Hong Ma, Sachin Jambawalikar, Dwight Aberle, Belinda D'Souza, Stuart Bentley-Hibbert, Monica Pernia Marin
来源: Journal of Translational Medicine

摘要:

缺氧、感染或身体损伤等因素造成的持续损伤可能会引起组织修复不当和结缔组织异常沉积,从而导致纤维化。这种现象可能发生在任何器官中,最终导致其功能障碍和最终衰竭。还发现组织纤维化是癌发生和癌症进展过程的核心。因此,及时诊断和定期监测对于实施旨在降低死亡率和提高整体生活质量的有效疾病缓解干预措施是必要的。虽然对这些主题进行了大量研究,但对它们之间的关系如何通过现代成像技术表现出来的全面理解仍有待建立。这项工作旨在提供与影响胸部器官的纤维化检测相关的成像技术的全面概述,并探索该领域未来潜在的进展。© 2024。作者。
Sustained injury from factors such as hypoxia, infection, or physical damage may provoke improper tissue repair and the anomalous deposition of connective tissue that causes fibrosis. This phenomenon may take place in any organ, ultimately leading to their dysfunction and eventual failure. Tissue fibrosis has also been found to be central in both the process of carcinogenesis and cancer progression. Thus, its prompt diagnosis and regular monitoring is necessary for implementing effective disease-modifying interventions aiming to reduce mortality and improve overall quality of life. While significant research has been conducted on these subjects, a comprehensive understanding of how their relationship manifests through modern imaging techniques remains to be established. This work intends to provide a comprehensive overview of imaging technologies relevant to the detection of fibrosis affecting thoracic organs as well as to explore potential future advancements in this field.© 2024. The Author(s).