纤维化放射学第二部分:腹部器官。
Radiology of fibrosis part II: abdominal organs.
发表日期:2024 Jul 02
作者:
Sofia Maria Tarchi, Mary Salvatore, Philip Lichtenstein, Thillai Sekar, Kathleen Capaccione, Lyndon Luk, Hiram Shaish, Jasnit Makkar, Elise Desperito, Jay Leb, Benjamin Navot, Jonathan Goldstein, Sherelle Laifer, Volkan Beylergil, Hong Ma, Sachin Jambawalikar, Dwight Aberle, Belinda D'Souza, Stuart Bentley-Hibbert, Monica Pernia Marin
来源:
Journal of Translational Medicine
摘要:
纤维化是由于缺氧、感染或物理损伤引起的持续组织损伤而导致的异常组织修复导致的结缔组织沉积的异常过程。它可以影响身体的几乎所有器官,导致功能障碍并最终导致器官衰竭。组织纤维化在癌发生和癌症进展中也起着至关重要的作用。器官纤维化的早期准确诊断以及充分的监测有助于实施早期疾病缓解干预措施,对于降低死亡率和提高生活质量非常重要。虽然已经对该主题进行了广泛的研究,但尚未建立对如何使用现代成像技术揭示这种关系的透彻理解。这项工作概述了腹部器官纤维化的表现方式,并列出了用于其检测的最相关的成像技术。讨论了新的成像技术和发展及其在器官纤维化早期检测中的有前景的应用。© 2024。作者。
Fibrosis is the aberrant process of connective tissue deposition from abnormal tissue repair in response to sustained tissue injury caused by hypoxia, infection, or physical damage. It can affect almost all organs in the body causing dysfunction and ultimate organ failure. Tissue fibrosis also plays a vital role in carcinogenesis and cancer progression. The early and accurate diagnosis of organ fibrosis along with adequate surveillance are helpful to implement early disease-modifying interventions, important to reduce mortality and improve quality of life. While extensive research has already been carried out on the topic, a thorough understanding of how this relationship reveals itself using modern imaging techniques has yet to be established. This work outlines the ways in which fibrosis shows up in abdominal organs and has listed the most relevant imaging technologies employed for its detection. New imaging technologies and developments are discussed along with their promising applications in the early detection of organ fibrosis.© 2024. The Author(s).