肿瘤模型的出现极大地促进了治疗药物和方法的发展。然而，由于其固有的复杂性，建立能够完全复制肿瘤组织情况的模型仍然极具挑战性。随着组织工程的发展，生物打印技术的进步促进了肿瘤模型的升级。本文重点介绍生物打印的最新进展，特别强调3D肿瘤模型的构建，并强调这两种技术的整合。此外，还讨论了相关技术的挑战和未来方向，同时也强调通过类似体外器官的3D肿瘤模型的出现来有效重建肿瘤微环境，从而加速新抗癌疗法的开发。© 2024 Yu et al 。

The development of therapeutic drugs and methods has been greatly facilitated by the emergence of tumor models. However, due to their inherent complexity, establishing a model that can fully replicate the tumor tissue situation remains extremely challenging. With the development of tissue engineering, the advancement of bioprinting technology has facilitated the upgrading of tumor models. This article focuses on the latest advancements in bioprinting, specifically highlighting the construction of 3D tumor models, and underscores the integration of these two technologies. Furthermore, it discusses the challenges and future directions of related techniques, while also emphasizing the effective recreation of the tumor microenvironment through the emergence of 3D tumor models that resemble in vitro organs, thereby accelerating the development of new anticancer therapies.© 2024 Yu et al.