在诊断和治疗之前，深部皮肤真菌病 (DCM) 和皮肤真菌感染可能会导致严重的发病率。在免疫功能低下的人群中，念珠菌属、曲霉属和镰刀菌属。真菌可引起这些感染，但皮肤癣菌，尤其是红色毛癣菌和须癣毛癣菌是最常见的。浅表红斑病变变成坚硬的皮下结节、溃疡、脓肿或窦道。在晚期病例中，扩张型心肌病可导致骨髓炎和骨质流失。 DCM 包括足菌肿，一种皮肤、皮下组织和骨骼的慢性传染病。在某些地区，它是一种地方病，可能类似于皮肤结核或癌性病变，导致诊断困难。临床表现、放射学检查结果和微生物培养可用于诊断，分子方法有助于培养阴性病例。一名免疫功能正常的农民，其手腕病变最初被怀疑为皮肤鳞状细胞癌，经组织学诊断为真菌瘤，强调了在高危个体中考虑深部真菌病及其异质临床表现的重要性。版权所有 © 2024，作者。

Deep cutaneous mycoses (DCMs) and skin fungal infections can cause significant morbidity until diagnosed and treated. In immunocompromised people, Candida spp., Aspergillus spp., and Fusarium spp. fungi can cause these infections, but dermatophytes, especially Trichophyton rubrum and T. mentagrophytes, are the most common. Superficial erythematous lesions become firm subcutaneous nodules, ulcers, abscesses, or sinus tracts. In advanced cases, DCMs can cause osteomyelitis and bone loss. DCM included mycetoma, a chronic infectious disease of the skin, subcutaneous tissues, and bones. In some areas, it is endemic and can mimic cutaneous tuberculosis or cancerous lesions, making diagnosis difficult. Clinical presentation, radiological findings, and microbiological culture are used to diagnose with molecular methods helping in culture-negative cases. An immunocompetent farmer with a wrist lesion initially suspected as cutaneous squamous cell carcinoma was histologically diagnosed as eumycetoma, emphasizing the importance of considering deep mycoses in high-risk individuals and their heterogeneous clinical presentation.Copyright © 2024, the Author(s).