研究动态
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三级医院肺癌患者特征的三年回顾。

A three-year review of lung cancer patient characteristics in a tertiary hospital.

发表日期:2023 Sep
作者: Jane S Afriyie-Mensah, Ernest Kwarteng, John Tetteh, Hafi Gbadamosi, Mary-Ann Dadzie, Yaw Boakye Mensah, Ekow Entsua-Mensah
来源: PHARMACOLOGY & THERAPEUTICS

摘要:

该研究旨在确定三级机构中一组肺癌患者的临床特征和组织学亚型。对呼吸科诊所 3 年期间经组织学确诊的肺癌病例的医疗记录进行回顾性审查。呼吸科诊所,Korle -加纳阿克拉Bu教学医院。所有组织学诊断为肺癌的成年患者均纳入研究。肺癌组织学类型。肺癌病例比例为12.4%。大多数是女性 (57.8%),诊断时的平均年龄为 55.8±16.0 岁。患者主要是不吸烟者(61%)。常见症状是慢性咳嗽和胸痛。超过三分之二的病例处于临床 III 期和 IV 期,吸烟者和非吸烟者的主要组织学亚型是腺癌。表皮生长因子受体 (EGFR) 和间变性淋巴瘤激酶 (ALK) 突变的基因检测基本缺失。大多数肺癌患者晚期就诊。腺癌是主要不吸烟人群中的主要组织学亚型,60 岁以下女性的患病率有所增加。这应该鼓励基因突变测试以提高患者的生存率。未声明。版权所有 © 作者。
The study sought to determine clinical characteristics and histologic subtypes of a cohort of lung cancer patients in a tertiary facility.Retrospective review of the medical records of histology-confirmed lung cancer cases at the respiratory clinic over a 3-year period.Respiratory Clinic, Korle-Bu Teaching Hospital, Accra, Ghana.All adult patients with histologically diagnosed lung cancer were enrolled.Lung cancer histological types.The proportion of lung cancer cases was 12.4%. The majority were women (57.8%) and the mean age at diagnosis was 55.8±16.0 years. The patients were predominantly non-smokers (61%). Common symptoms were chronic cough and chest pain. More than two-thirds of the cases presented in clinical stages III and IV with the predominant histological subtype being adenocarcinoma in smokers and non-smokers. Genetic testing for epidermal growth factor receptor (EGFR) and Anaplastic Lymphoma kinase (ALK) mutations were largely absent.The majority of lung cancer patients presented late with advanced disease. Adenocarcinoma was the predominant histological subtype in a predominantly non-smoking population, with an increased prevalence among women less than 60 years. This should encourage testing for genetic mutations to improve patient survival.None declared.Copyright © The Author(s).