氧化镁纳米粒子 (MgONPs) 可以通过多种方法制备，包括绿色化学方法，因为其具有多种应用和多功能特性。当前的研究旨在利用废柚子皮提取物 (CP-MgONPs) 制备一种方便、生物相容且经济可行的 MgONPs CP-MgONPs是通过可持续的方法从废柚子皮提取物中合成的，既作为封端剂又作为还原剂，不使用任何有害物质。形成的 CP-MgONP 的物理化学特征通过复杂的分析和显微技术确定。对生物 CP-MgONPs 的抗菌、抗癌和光催化特性进行了检测。紫外-可见光谱中 284 nm 处的显着吸收峰是 CP-MgONPs 的显着特征。扫描电子显微镜（SEM）显示纳米粒子的多面体形态，并有轻微的 CP-MgONPs 团聚。 CP-MgONPs 对六种细菌菌株表现出优异的抗菌效力。 CP-MgONPs 对大肠杆菌 (20.72±0.33mm) 和金黄色葡萄球菌 (19.52±0.05mm) 表现出显着的敏感性，抑制区最高。 CP-MgONPs对HepG2（IC50 ： 15.3 μg·mL-1）癌细胞的抗癌作用进行了评估，并显示出潜在的抗癌活性。在用 CP-MgONP 处理的细胞中观察到细胞损伤的迅速逆转，表现为细胞膜完整性受损、细胞凋亡和氧化应激。生物合成的 CP-MgONPs 在使用酸性橙 8 (AO-8) 染料的紫外光下也具有与 MgO 粉末一样的成功光催化潜力。 CP-MgONPs 的降解性能显示，短时间内对酸性橙 8 (AO-8) 染料的光催化降解效率超过 94%。这项研究结果表明，生物源 CP-MgONPs 在低浓度下可能具有优势，并对环境产生积极影响.版权所有 © 2024 Nawal M. Al Musayeib 等人。

Magnesium oxide nanoparticles (MgONPs) have been fabricated by several approaches, including green chemistry approach due to diverse application and versatile features.The current study aimed to prepare a convenient, biocompatible, and economically viable MgONPs using waste citron peel extract (CP-MgONPs) to evaluate their biological applications.The CP-MgONPs were synthesized by a sustainable approach from extract of waste citron peel both as capping and reducing agents without use of any hazardous material. The physicochemical features of formed CP-MgONPs were determined by sophisticated analytical and microscopic techniques. The biogenic CP-MgONPs were examined for their antibacterial, anticarcinogenic, and photocatalytic attributes.A prominent absorption peak in the UV-Vis spectra at 284 nm was the distinguishing characteristic of the CP-MgONPs. The scanning electron microscopy (SEM) reveals polyhedral morphology of nanoparticles with slight agglomeration of CP-MgONPs. The CP-MgONPs exerted excellent antibacterial potencies against six bacterial strains. The CP-MgONPs displayed significant susceptibility towards E. coli (20.72 ± 0.33 mm) and S. aureus (19.52 ± 0.05 mm) with the highest inhibition zones. The anticancer effect of CP-MgONPs was evaluated against HepG2 (IC50 : 15.3 μg·mL-1) cancer cells and exhibited potential anticancer activity. A prompt inversion of cellular injury manifested as impairment of the integrity of the cell membrane, apoptosis, and oxidative stress was observed in treated cells with CP-MgONPs. The biosynthesized CP-MgONPs also conducted successful photocatalytic potential as much as MgO powder under the UV-light using acid orange 8 (AO-8) dye. The degradation performance of CP-MgONPs showed over 94% photocatalytic degradation efficiency of acid orange 8 (AO-8) dyes within a short time.Outcomes of this research signify that biogenic CP-MgONPs may be advantageous at low concentrations, with positive environmental impacts.Copyright © 2024 Nawal M. Al Musayeib et al.