结节性红斑 (EN) 是一种非特异性结节性皮下皮疹，其特征是在对不同的内部和外部抗原产生非特异性反应后突然出现疼痛性肿块，特别是在腿部。无论病因如何，临床和组织学表现都是固定的。结节性红斑最常与感染有关，尤其是细菌感染，较少见的是病毒、真菌和寄生虫感染。可以讨论其他情况，包括全身性疾病、恶性肿瘤、药物和疫苗。 在几乎一半的病例中，如果没有找到原因，结节性红斑是特发性的。我们报告了一例七岁男性因沙门氏菌感染继发结节性红斑的病例。我们观察的特点是在胃肠道症状之前首先出现全身症状。版权所有 © 2024，Benhachem 等人。

Erythema nodosum (EN) is a non-specific nodular dermo-hypodermic rash characterized by the sudden occurrence of painful lumps located especially in the legs following a non-specific reaction to different internal and external antigens. Clinical and histological manifestations are stereotyped, regardless of the etiology. Erythema nodosum is most frequently associated with infections, particularly bacterial and less commonly viral, fungal, and parasitic. Other conditions can be discussed, including systemic diseases, malignant tumors, medicines, and vaccines. In almost half of cases, erythema nodosum is idiopathic if no cause is found. We report a case of erythema nodosum secondary to a Salmonella infection in a seven-year-old male. The peculiarity of our observation is the initial presentation of systemic signs that preceded the gastrointestinal symptoms.Copyright © 2024, Benhachem et al.