在口腔疾病中，口腔癌是导致死亡的主要原因，并构成严重的健康风险。原发肿瘤（T）-区域淋巴结（N）-远处转移（M）组成（TNM）分期对于口腔鳞状细胞癌（OSCC）患者的治疗策略规划至关重要。本研究评估了临床TNM分期的预测准确性在机构环境中对 OSCC 进行组织病理学分期 (pTNM)。对 54 个连续组织学确诊、手术治疗的 OSCC 病例进行了 TNM 分期评估。该研究将手术时的临床分期与切除活检报告中获得的病理分期进行了比较。 Microsoft Excel（Microsoft® Corp.，雷蒙德，华盛顿州，美国）用于数据编译和描述性分析。卡方检验、方差分析 (ANOVA) 和 Tukey 诚实显着性差异 (HSD) 事后检验用于使用社会科学统计包 (IBM SPSS Statistics for Windows) 比较数据的统计显着性，p 值 <0.05 ，IBM Corp.，版本 23.0，Armonk，NY）。牙槽粘膜（n=22，40.74%）是最常发生的部位，其次是舌头（n=17，31.48%）。在纳入的 54 例病例中，根据临床肿瘤大小，分为 T1（n=6）、T2（n=13）、T3（n=13）、T4a（n=16）和 T4b（n=6）。 T2 肿瘤通常被下期 (n=7)，而 T4a (n=8) 肿瘤最常被下期。 T4a (n=8) 临床分期和组织病理学分期之间的一致性最好，其次是 T2、T3 和 T1。在节点状态中，N1 显示出最大的变化。卡方检验显示肿瘤大小比较（p <0.001）和淋巴结状态比较（p=0.002）有统计学显着性。方差分析测试没有显示任何统计显着性。 Tukey 的 HSD 事后检验显示 N0 和 N1 状态有统计显着性 (p=0.034)。 N0 和 N1 显示出最高的一致性，其次是 N2b。术前放射学和临床评估对于决定患者的治疗过程至关重要。然而，并非所有患者都需要X光片来确定肿瘤大小或淋巴结状态评估。准确的诊断对于 OSCC 的治疗计划至关重要。版权所有 © 2024, S et al.

Among oral diseases, oral cancer is the primary cause of death and poses a serious health risk. Primary tumor (T) - regional lymph node (N) - distant metastasis (M) comprising (TNM) staging is crucial for planning treatment strategies for patients with oral squamous cell carcinoma (OSCC).This study evaluated the predictive accuracy of clinical TNM staging of OSCC to histopathological staging (pTNM) in an institutional setting.Fifty-four consecutive histologically confirmed, surgically treated OSCC cases were evaluated for TNM staging. The study compared the clinical staging at the time of surgery with the pathological staging obtained from excisional biopsy reports. Microsoft Excel (Microsoft® Corp., Redmond, WA, USA) was used for the data compilation and descriptive analysis. The chi-square test, analysis of variance (ANOVA), and Tukey's Honest Significant Difference (HSD) posthoc test were used to compare the data for statistical significance with p value <0.05 using Statistical Package for the Social Sciences (IBM SPSS Statistics for Windows, IBM Corp., Version 23.0, Armonk, NY).The alveolar mucosa (n=22, 40.74%) was the most frequently occurring site, followed by the tongue (n=17, 31.48%). Out of the 54 included cases, based on clinical tumor size, there were T1 (n=6), T2 (n=13), T3 (n=13), T4a (n=16) and T4b (n=6). T2 tumors were usually upstaged (n=7) while T4a (n=8) tumors were most often downstaged. T4a (n=8) had the best concordance between clinical and histopathological staging, followed by T2, T3, and T1. In nodal status, N1 showed the most variation. The chi-squared test showed statistical significance for tumor size comparison (p <0.001) and nodal status comparison (p=0.002). ANOVA test did not show any statistical significance. Tukey's HSD posthoc test showed statistical significance (p=0.034) for N0 and N1 status. The highest concordance was shown by N0 and N1 followed by N2b.Preoperative radiological and clinical assessments are essential for deciding on a patient's course of treatment. However, not all patients may require radiographs to determine tumor size or nodal status assessment. Accurate diagnosis is vital for the treatment planning of OSCC.Copyright © 2024, S et al.