研究动态
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硒纳米粒子的无化学、生物嵌入,用于有机污染物降解的高度加速光响应及其体外抗菌剂、抗氧化剂作用、细胞毒性分析。

Chemical free, bio-Intercalation of selenium nanoparticles for highly accelerated photo-responsive of organic contaminants debasement and their in-vitro anti-bacterial agents, anti-oxidants effect, cyto-toxic analysis.

发表日期:2024 Jul 02
作者: Janani Rajendran, Prasanna Jeyaraman, Elamathi Sakthivel, Abdulrahman I Almansour, Natarajan Arumugam, Pandian Bothi Raja
来源: ANTIOXIDANTS & REDOX SIGNALING

摘要:

本研究探讨了使用 Excoecaria agallocha 叶子作为插入硒纳米颗粒 (SeNP) 的生物模板。使用 SEM-EDX、TEM/HR-TEM 和 XRD 光谱研究等技术对合成的 SeNP 进行表征。研究发现,SeNPs在50μL/mL剂量时表现出最大的清洁能力,对DPPH自由基的抑制率为95%。然而,在 300μg/L 浓度下,72 小时内细胞吸收率仅限于 55%。合成的 SeNPs 还表现出对 MCF-7 乳腺癌细胞系的强烈细胞毒性作用,表明它们作为抗癌药物的潜力。需要进一步研究来充分探索这些新型纳米复合材料的潜力。版权所有 © 2024。由 Elsevier Inc. 出版。
This study investigates the use of Excoecaria agallocha leaves as a bio-template for the intercalation of Selenium nanoparticles (SeNPs). The synthesized SeNPs were characterized using techniques like SEM-EDX, TEM/HR-TEM, and XRD spectroscopic studies. The study found that SeNPs showed maximum cleaning ability at a dosage of 50 μL/mL, with 95% inhibition of DPPH radicals. However, cellular absorption was limited to 55% at concentrations of 300μg/L over a 72-hour period. The synthesized SeNPs also demonstrated a strong cytotoxic effect on MCF-7 breast cancer cell lines, indicating their potential as anti-cancer agents. Further research is needed to fully explore the potential of these novel nanocomposites.Copyright © 2024. Published by Elsevier Inc.