泌尿生殖系统癌症相关死亡率的社会人口统计学差异尚未得到充分研究，特别是在多种癌症类型之间。本研究旨在调查美国最常见泌尿生殖系统癌症死亡率的性别、种族和地理差异。前列腺癌、膀胱癌、肾癌和睾丸癌的死亡率数据来自疾病控制和预防中心 (CDC) ) 1999 年至 2020 年间的 WONDER 数据库。按年份、性别、种族、城乡状况和地理区域对年龄调整死亡率 (AAMR) 进行分析，显着性水平为 p < 0.05。总体而言，前列腺、膀胱、和肾癌显着下降，而睾丸癌相关死亡率保持稳定。男性膀胱癌和肾癌的 AAMR 比女性高 3-4 倍。黑人/非裔美国人的前列腺癌死亡率最高，并在 2015 年之后开始上升。白人、黑人、非裔美国人和亚裔/太平洋岛民的膀胱癌死亡率显着下降，但美洲印第安人/阿拉斯加原住民的死亡率保持稳定。白人的肾癌相关死亡率最高，但其他种族的死亡率显着下降。白人睾丸癌死亡率显着增加，但黑人和非裔美国人的死亡率保持稳定。大都市地区的泌尿生殖系统癌症死亡率下降，但非大都市地区的死亡率要么上升（膀胱癌和睾丸癌），要么保持稳定（肾癌）。中西部地区前列腺癌和肾癌死亡率最高，南部地区膀胱癌死亡率最高，西部地区睾丸癌死亡率最高。美国泌尿生殖系统癌症的死亡率趋势存在显着的社会人口差异。这些发现强调需要有针对性的干预措施和进一步研究，以解决这些差异并改善所有受泌尿生殖系统癌症影响的人群的结果。版权所有 © 2024 Ghazwani, Alghafees, Suheb, Shafqat, Sabbah, Arabi, Razak, Sabbah, Alaswad, AlKattan, Ouban 、阿卜杜勒·拉布、肖瓦夫、阿尔哈米斯、阿拉斯克、阿尔哈亚尔、阿尔赛汗、阿达尔、阿尔多萨里、阿尔库拉希和穆萨利。

Sociodemographic disparities in genitourinary cancer-related mortality have been insufficiently studied, particularly across multiple cancer types. This study aimed to investigate gender, racial, and geographic disparities in mortality rates for the most common genitourinary cancers in the United States.Mortality data for prostate, bladder, kidney, and testicular cancers were obtained from the Centers for Disease Control and Prevention (CDC) WONDER database between 1999 and 2020. Age-adjusted mortality rates (AAMRs) were analyzed by year, gender, race, urban-rural status, and geographic region using a significance level of p < 0.05.Overall, AAMRs for prostate, bladder, and kidney cancer declined significantly, while testicular cancer-related mortality remained stable. Bladder and kidney cancer AAMRs were 3-4 times higher in males than females. Prostate cancer mortality was highest in black individuals/African Americans and began increasing after 2015. Bladder cancer mortality decreased significantly in White individuals, Black individuals, African Americans, and Asians/Pacific Islanders but remained stable in American Indian/Alaska Natives. Kidney cancer-related mortality was highest in White individuals but declined significantly in other races. Testicular cancer mortality increased significantly in White individuals but remained stable in Black individuals and African Americans. Genitourinary cancer mortality decreased in metropolitan areas but either increased (bladder and testicular cancer) or remained stable (kidney cancer) in non-metropolitan areas. Prostate and kidney cancer mortality was highest in the Midwest, bladder cancer in the South, and testicular cancer in the West.Significant sociodemographic disparities exist in the mortality trends of genitourinary cancers in the United States. These findings highlight the need for targeted interventions and further research to address these disparities and improve outcomes for all populations affected by genitourinary cancers.Copyright © 2024 Ghazwani, Alghafees, Suheb, Shafqat, Sabbah, Arabi, Razak, Sabbah, Alaswad, AlKattan, Ouban, Abdul Rab, Shawwaf, AlKhamees, Alasker, Al-Khayal, Alsaikhan, Addar, Aldosari, Al Qurashi and Musalli.