我们报告了一例罕见的 18F-FDG PET/CT 上类似恶性肿瘤的髓内脊髓软斑病病例。一名 61 岁男性接受了对比增强脊髓 MRI，以评估 1 周的进行性左侧肌无力。脊髓 MRI 显示 C5 水平颈髓内有 1.3 厘米增强肿块，伴有脊髓水肿。随后，进行 18F-FDG PET/CT 进行评估。图像显示脊髓中有一个界限清楚的代谢亢进肿块；没有病变提示恶性肿瘤或转移。进行了肿瘤次全切除；组织病理学检查发现软斑。这强调了组织病理学评估的重要性和诊断确认的重要性。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。

We report a rare case of intramedullary spinal cord malakoplakia mimicking malignancy on 18F-FDG PET/CT. A 61-year-old man underwent a contrast-enhanced spinal cord MRI to evaluate 1 week of progressive left-sided weakness. Spinal cord MRI showed a 1.3-cm enhancing intramedullary cervical spinal cord mass at C5 level with cord edema. Subsequently, 18F-FDG PET/CT was performed for evaluation. The images showed a well-circumscribed hypermetabolic mass in the spinal cord; no lesions were suggestive of malignancy or metastasis. A subtotal tumor excision was performed; histopathological examination revealed malakoplakia. This emphasizes the significance of histopathological evaluation and the importance of diagnostic confirmation.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.