研究动态
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基于网络的口腔舌癌预后工具:在线预测因子分析。

Web-based prognostic tools for oral tongue cancer: An analysis of online predictors.

发表日期:2024 Jul 05
作者: Awais Wahab, Ibrahim O Bello, Rasheed Omobolaji Alabi, Marco Mascitti, Giuseppe Troiano, Matti Mauramo, Ricardo D Coletta, Tuula Salo, Alhadi Almangush
来源: BIOMEDICINE & PHARMACOTHERAPY

摘要:

口腔舌鳞状细胞癌(OTSCC)通常表现为侵袭性临床行为,可能需要基于可靠预后的多学科治疗。我们旨在评估五种基于网络的在线工具预测 OTSCC 切除和活检样本临床行为的预后能力。总共纳入了 135 个 OTSCC 切除病例和 33 个 OTSCC 活检样本来预测复发和生存。受试者工作特征曲线 (AUC) 下的面积、χ2 检验和校准图旨在估计每个工具的预后能力。名为“早期 OTSCC 局部复发风险预测”的工具的准确度为 82%。工具“头”
Oral tongue squamous cell carcinoma (OTSCC) often presents with aggressive clinical behaviour that may require multimodality treatment based on reliable prognostication. We aimed to evaluate the prognostic ability of five online web-based tools to predict the clinical behaviour of OTSCC resection and biopsy samples.A total of 135 OTSCC resection cases and 33 OTSCC biopsies were included to predict recurrence and survival. Area under the receiver operating characteristic curves (AUC), χ2 tests, and calibration plots constructed to estimate the prognostic power of each tool.The tool entitled 'Prediction of risk of Locoregional Recurrences in Early OTSCC' presented an accuracy of 82%. The tool, 'Head & Neck Cancer Outcome Calculator' for 10-year cancer-related mortality had an accuracy 77% and AUC 0.858. The other tool entitled 'Cancer Survival Rates' for 5-year mortality showed an accuracy of 74% and AUC of 0.723. For biopsy samples, 'Cancer Survival Prediction Calculators' predicted the recurrence free survival with an accuracy of 70%.Web-based tools can aid in clinical decision making of OTSCC. Three of five online web-based tools could predict recurrence risk and cancer-related mortality in resected OTSCC and one tool could help in clinical decision making for biopsy samples.© 2024 The Author(s). Oral Diseases published by Wiley Periodicals LLC.