收入较低与心血管疾病 (CVD) 和死亡率高发有关。 CVD 是癌症幸存者发病和死亡的重要原因。然而，关于这一人群的收入、CVD 和死亡率之间关系的研究有限。这项研究利用了国家健康和营养检查调查 (NHANES) 的全国代表性数据，这是一项评估人群健康和营养状况的横断面调查。美国人口。我们的研究包括 2003 年至 2014 年年龄≥20 岁的 NHANES 参与者，他们自我报告了癌症病史。我们评估了收入水平、CVD 患病率和全因死亡率之间的关联。全因死亡率数据是通过公众使用的死亡率档案获得的。收入水平是通过贫困收入比（PIR）来评估的，贫困收入比是通过家庭（或个人）收入除以贫困线来计算的。我们通过后向消除法使用多变量调整的 Cox 比例风险模型来评估癌症幸存者的 PIR、CVD 和全因死亡率之间的关联。该队列包括 2,464 名癌症幸存者，平均年龄为 62 岁（42% 为男性）。与具有较高 PIR 三分位数的个体相比，处于最低 PIR 三分位数的个体先前存在 CVD 和后天性 CVD 的比例较高。在患有后天性 CVD 的参与者中，与最高 PIR 三分位数相比，最低 PIR 三分位数的风险死亡率增加了两倍以上（风险比 (HR) = 2.17；95% CI：1.27-3.71）。此外，我们发现 PIR 与 CVD 一样，都是癌症幸存者死亡率的有力预测因子。在没有 CVD 的患者中，与最高 PIR 三分位数的参考相比，最低 PIR 三分位数的死亡风险几乎增加了两倍（HR = 1.72；95% CI：1.69-4.35）。对癌症幸存者的研究表明，低 PIR 与较高的 CVD 患病率相关。低 PIR 还与癌症幸存者死亡风险增加相关，显示出与先前存在和后天性 CVD 的影响相当。需要紧急公共卫生资源来进一步研究和改善这一高危人群的筛查和获得护理的机会。版权所有：© 2024 Yogeswaran 等人。这是一篇根据知识共享署名许可条款分发的开放获取文章，允许在任何媒体上不受限制地使用、分发和复制，前提是注明原始作者和来源。

Lower income is associated with high incident cardiovascular disease (CVD) and mortality. CVD is an important cause of morbidity and mortality in cancer survivors. However, there is limited research on the association between income, CVD, and mortality in this population.This study utilized nationally representative data from the National Health and Nutrition Examination Survey (NHANES), a cross-sectional survey evaluating the health and nutritional status of the US population. Our study included NHANES participants aged ≥20 years from 2003-2014, who self-reported a history of cancer. We evaluated the association between income level, prevalence of CVD, and all-cause mortality. All-cause mortality data was obtained through public use mortality files. Income level was assessed by poverty-income ratio (PIR) that was calculated by dividing family (or individual) income by poverty guideline. We used multivariable-adjusted Cox proportional hazard models through a backward elimination method to evaluate associations between PIR, CVD, and all-cause mortality in cancer survivors.This cohort included 2,464 cancer survivors with a mean age of 62 (42% male) years. Compared with individuals with a higher PIR tertiles, those in the lowest PIR tertile had a higher rate of pre-existing CVD and post-acquired CVD. In participants with post-acquired CVD, the lowest PIR tertile had over two-fold increased risk mortality (Hazard Ratio (HR) = 2.17; 95% CI: 1.27-3.71) when compared to the highest PIR tertile. Additionally, we found that PIR was as strong a predictor of mortality in cancer survivors as CVD. In patients with no CVD, the lowest PIR tertile continued to have almost a two-fold increased risk of mortality (HR = 1.72; 95% CI: 1.69-4.35) when compared to a reference of the highest PIR tertile.In this large national study of cancer survivors, low PIR is associated with a higher prevalence of CVD. Low PIR is also associated with an increased risk of mortality in cancer survivors, showing a comparable impact to that of pre-existing and post-acquired CVD. Urgent public health resources are needed to further study and improve screening and access to care in this high-risk population.Copyright: © 2024 Yogeswaran et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.