研究动态
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组蛋白去甲基化通过先天免疫来抑制白血病。

Histone demethylation tones down leukemia through innate immunity.

发表日期:2024 Jul 05
作者: Andre Monteleone, Gabriel K Griffin
来源: Immunity & Ageing

摘要:

PHF8 引起的组蛋白去甲基化启动了急性髓系白血病的先天免疫信号传导,阐明了一种新的治疗策略。
Histone demethylation by PHF8 initiates innate immune signaling in acute myeloid leukemia, elucidating a novel therapeutic strategy.