组蛋白去甲基化通过先天免疫来抑制白血病。
Histone demethylation tones down leukemia through innate immunity.
发表日期:2024 Jul 05
作者:
Andre Monteleone, Gabriel K Griffin
来源:
Immunity & Ageing
摘要:
PHF8 引起的组蛋白去甲基化启动了急性髓系白血病的先天免疫信号传导,阐明了一种新的治疗策略。
Histone demethylation by PHF8 initiates innate immune signaling in acute myeloid leukemia, elucidating a novel therapeutic strategy.