本研究探讨鼻空肠和静脉营养对上消化道狭窄患者补充营养的有效性，并分析营养不良的危险因素，为临床营养策略提供参考。对2015年1月至2023年1月接受营养支持的71例食管癌和胃癌引起的上消化道狭窄患者进行回顾性分析。其中53例患者有完整的基线和随访数据。我们收集了一般临床和围手术期数据，以比较鼻空肠营养和静脉营养的疗效。使用单变量和多变量逻辑回归分析营养不良的危险因素。 24.53%（13/53）的上消化道狭窄患者出现营养不良。鼻空肠营养组营养不良发生率为6.06%（2/33），静脉营养组营养不良发生率为55.00%（11/20），差异有统计学意义（P < .001）。单变量和多变量回归分析确定糖尿病（P < .001）、初始血K（P = .011）、病理分期（P < .001）和病理分级（P < .001）是患有以下疾病的患者营养不良的危险因素：上消化道狭窄。糖尿病 (P = .028)、初始血 K (P = .018) 和病理分期 (P = .011) 被发现是独立危险因素。与静脉营养相比，上消化道狭窄患者经鼻空肠营养可降低营养不良的发生率。糖尿病、初始血 K、病理分期和病理分级是营养不良的危险因素，其中糖尿病、初始血 K 和病理分期是独立的危险因素。版权所有 © 2024 作者。由 Wolters Kluwer Health, Inc. 出版

This study examines the effectiveness of nasojejunal and intravenous nutrition in supplementing nutrition for patients with upper gastrointestinal (GI) strictures and analyzes the risk factors associated with malnutrition to provide references for clinical nutrition strategies. A retrospective analysis was conducted on 71 patients with upper GI strictures caused by esophageal and gastric cancers, who received nutritional support from January 2015 to January 2023. Out of these, 53 patients had complete baseline and follow-up data. We collected general clinical and perioperative data for comparison of the efficacy between nasojejunal nutrition and intravenous nutrition. Risk factors for malnutrition were analyzed using univariate and multivariate logistic regression. Malnutrition occurred in 24.53% (13/53) of the patients with upper GI strictures. The incidence of malnutrition was 6.06% (2/33) in the nasojejunal nutrition group compared to 55.00% (11/20) in the intravenous nutrition group, with a statistically significant difference (P < .001). Univariate and multivariate regression analyses identified diabetes (P < .001), initial blood K (P = .011), pathological staging (P < .001), and pathological grading (P < .001) as risk factors for malnutrition in patients with upper GI strictures. Diabetes (P = .028), initial blood K (P = .018), and pathological staging (P = .011) were found to be independent risk factors. Nasojejunal nutrition results in a lower incidence of malnutrition compared to intravenous nutrition in patients with upper GI strictures. Diabetes, initial blood K, pathological staging, and pathological grading are risk factors for malnutrition, with diabetes, initial blood K, and pathological staging serving as independent risk factors.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.