骨骼是埃德海姆-切斯特病最常见的部位。在影像学上，Erdheim-Chester 病的骨受累通常表现为骨硬化病变，溶骨性病变并不常见。很少有报道显示骨病变没有或细微的结构变化。我们描述了一例伴有非典型骨受累的 Erdheim-Chester 病病例的 FDG PET/CT 结果。骨病变在X线和CT上显示没有或细微的结构变化，没有明显的骨硬化或骨溶解，并且FDG活性增加，类似于淋巴瘤。熟悉 Erdheim-Chester 病骨受累的这些非典型影像学表现有助于诊断。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。

Bones are the most common sites involved in Erdheim-Chester disease. On imaging, the bone involvement in Erdheim-Chester disease typically presents as osteosclerotic lesions, and osteolytic lesions are unusual. Bone lesions showing no or subtle structure changes are rarely reported. We describe FDG PET/CT findings in a case of Erdheim-Chester disease with atypical bone involvement. The bone lesions showed no or subtle structure changes without obvious osteosclerosis or osteolysis on radiographs and CT, and increased FDG activity mimicking lymphoma. Familiarity with these atypical imaging findings of bone involvement in Erdheim-Chester disease is helpful for the diagnosis.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.