目前的指南建议不要使用常规影像学检查来检测无症状乳腺癌患者的远处转移。然而，有效治疗方法和诊断准确性的最新进展提出了重新评估强化转移监测的临床疗效的必要性。我们报告了一项多中心回顾性研究的结果，以调查强化影像学研究与生存结果之间的关联。我们回顾性审查了 2010 年 1 月至 2011 年 12 月期间在韩国 11 家医院接受手术的 4130 名患者的数据。患者被分为两组基于无病期间转移影像学研究的强度。影像学研究的类型和间隔取决于每位医生的决定。高强度筛查显示无远处转移生存期较短[p < 0.001，风险比 (HR) 1.62； 95% 置信区间 (CI) 1.29-2.04]，特别是对于骨或肺是第一个转移部位的患者。中位随访期为 110.0 个月，5 年乳腺癌特异性生存率 (BCSS) 为 96.5%。与低强度筛查组相比，高强度筛查组的 BCSS 显着较差（p < 0.001，HR 3.13；95% CI 2.32-4.21）。然而，多变量分析和倾向评分匹配分析均显示筛查强度与 BCSS 之间没有显着关联。检测远处转移的频繁影像学研究与远处转移的早期检测相关，尤其是肺转移和骨转移。然而，尽管使用了当前可用的治疗方法，但密集监测显示与 BCSS 没有明显关联。© 2024。作者。

Current guidelines recommend against the use of routine imaging tests to detect distant metastasis in asymptomatic breast cancer patients. However, recent advancements in effective therapeutics and diagnostic accuracy have raised the need to reassess the clinical efficacy of intensive metastasis surveillance. We report the results of a multicenter retrospective study to investigate the association between intensive imaging studies and survival outcomes.We retrospectively reviewed the data of 4130 patients who underwent surgery from 11 hospitals in Korea between January 2010 and December 2011. Patients were divided into two groups on the basis of the intensity of metastasis imaging studies during their disease-free period. The types and intervals of the imaging studies were based on each physician's decisions.High-intensive screening showed a shorter distant metastasis-free survival [p < 0.001, hazard ratio (HR) 1.62; 95% confidence interval (CI) 1.29-2.04], especially for patients in whom bone or lung was the first site of metastasis. With a median follow-up period of 110.0 months, the 5-year breast cancer-specific survival (BCSS) rate was 96.5%. The high-intensity screening group showed significantly poorer BCSS compared with the low-intensity screening group (p < 0.001, HR 3.13; 95% CI 2.32-4.21). However, both multivariable analysis and propensity score matching analysis showed no significant association between the screening intensity and BCSS.Frequent imaging studies to detect distant metastasis were associated with earlier detection of distant metastasis, especially for lung and bone metastasis. However, intensive surveillance showed no apparent association with BCSS despite the use of currently available treatments.© 2024. The Author(s).