研究动态
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支气管内超声检查用于评估接受根治性放化疗的 cT4b 食管癌患者的气管支气管树浸润:评估可切除性。

Endobronchial Ultrasonography to Assess and Evaluate Tracheobronchial Tree Invasion in cT4b Esophageal Cancer Patients Treated with Definitive Chemoradiotherapy: Assessment of Resectability.

发表日期:2024 Jul 06
作者: I L Defize, E M de Groot, O van de Langerijt, M van Velzen, S Mook, N Haj Mohammad, M Bulbul, J P Ruurda, R van Hillegersberg
来源: ANNALS OF SURGICAL ONCOLOGY

摘要:

在 cT4b 食管癌中,准确评估根治性放化疗 (dCRT) 后气管支气管树侵犯有助于选择可以进行肿瘤根治性食管切除术的患者。本报告旨在确定支气管内超声评估 cT4b 食管癌患者 dCRT 后气管支气管树肿瘤侵犯的准确性。在诊断性增强计算机断层扫描 (CT) 上怀疑气管支气管树侵犯的食管癌患者接受了分期支气管内超声检查(EBUS)有资格纳入本研究。为了评估 EBUS 在评估 dCRT 后气管支气管树内肿瘤向内生长的准确性,在重新分期期间接受 EBUS 并接受手术的患者被纳入最终分析。最终分析包括 26 名患者。 20 名患者中,有 18 名 (90%) 在 EBUS 重新分期中恢复了气管支气管树的解剖结构,并且认为不存在肿瘤侵袭,因此实现了根治性食管切除术。在 6 名患者中,在 EBUS 重新分期期间观察到持续向内生长。对于这些患者,平均 9 周后重复进行 EBUS。 4 名患者被认为不存在肿瘤侵袭,其中 3 名患者实现了根治性切除。EBUS 为评估 cT4b 食管癌患者 dCRT 后气管支气管树侵袭的评估提供了有价值的信息。这些信息可以帮助正确选择受益于治愈性但高侵入性食管切除术的患者。© 2024。作者。
In cT4b esophageal cancer, accurate assessment of tracheobronchial tree invasion after definitive chemoradiotherapy (dCRT) aids in the selection of patients for whom an oncologic radical esophagectomy can be achieved. The current report aimed to determine the accuracy of endobronchial ultrasound in assessing tumor invasion in the tracheobronchial tree after dCRT in patients with cT4b esophageal cancer.Esophageal cancer patients with suspicion of tracheobronchial tree invasion on the diagnostic contrast-enhanced computed tomography (CT) who underwent a staging endobronchial ultrasonography (EBUS) were eligible for inclusion in this study. To assess the accuracy of the EBUS in assessing tumor ingrowth in the tracheobronchial tree after dCRT, patients who had an EBUS during restaging and underwent surgery were included in the final analysis.The final analysis included 26 patients. For 18 (90%) of 20 patients in whom the anatomy of the tracheobronchial tree was restored on the restaging EBUS and tumor invasion was considered to be absent, a radical esophagectomy was achieved. In six patients, persistent ingrowth was observed during the restaging EBUS. For these patients, the EBUS was repeated after a median of 9 weeks. Tumor invasion was considered to be absent in four patients, and a radical resection was achieved in three of these patients.The EBUS provides valuable information on the assessment of tracheobronchial tree invasion in cT4b esophageal cancer patients after dCRT. This information could aid in the proper selection of patients who benefit from a curative but highly invasive esophagectomy.© 2024. The Author(s).