杜仲 (Eucommia ulmoides Oliv)。杜仲是著名的天然药食两用植物，具有补肝肾、强筋骨、安胎等功效。越来越多的证据表明，杜仲中的多糖。 EUPs（Eups）是一类重要的、有代表性的生物活性大分子，在体内外具有多种促进健康的生物活性，如抗氧化活性、免疫调节活性、降血脂降血糖活性、抗炎活性、抗肿瘤活性、等等。该综述旨在全面、系统地整理近年来EUPs的提取纯化方法、结构特征、生物活性、作用机制、结构修饰和毒性等方面的研究进展，以支持其治疗潜力和保健功能。在结构表征和药理活性领域，还为 EUP 的未来研究提出了新的有价值的见解，以促进治疗剂和功能性食品的开发。版权所有 © 2024。由 Elsevier B.V. 出版。

Eucommia ulmoides Oliv. (tu-chung), as a famous nature medical and edible plant, has the effect of tonifying liver and kidney, strengthening the function of the muscles and bones, and miscarriage prevention. Accumulating evidence has demonstrated that the polysaccharides from Eucommia ulmoides Oliv. (EUPs) are a kind of vital and representative biologically active macromolecules and have various health-promoting biological activities in vivo and in vitro, such as antioxidant activity, immunomodulatory activity, hypolipidemic and hypoglycemic activities, anti-inflammatory activities, anti-tumor activity, and among others. The review aims to comprehensively and systematically collate the recent research progress on extraction and purification methods, structural characteristics, biological activities, mechanism of action, structural modification, and toxicity of EUPs to support their therapeutic potential and health-care functions. New valuable insights for future research with EUPs were also proposed in the areas of structural characterization and pharmacological activities to promoting the development of therapeutic agents and functional foods.Copyright © 2024. Published by Elsevier B.V.