前列腺特异性膜抗原 (PSMA) PET/CT 已成为诊断原发性和复发性前列腺腺癌的无与伦比的方法，通常可以揭示以前在常规成像中看不见的疾病部位。在这名疑似前列腺癌复发的 78 岁男性中，PSMA PET/CT 显示大脑中有局灶性放射性示踪剂摄取，这通常会引起对转移的怀疑，但在最近中风的情况下却是假阳性。据报道，亚急性梗塞以及原发性和继发性脑肿瘤中 PSMA 摄取增加。仔细询问病史并与既往影像学进行比较对于避免此类患者的假阳性诊断至关重要。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。

Prostate-specific membrane antigen (PSMA) PET/CT has become an unparalleled modality in the diagnosis of primary and recurrent prostatic adenocarcinoma, often revealing sites of disease that were previously invisible on conventional imaging. In this 78-year-old man with suspected prostate cancer recurrence, PSMA PET/CT revealed focal radiotracer uptake in the brain, which would ordinarily raise suspicion for metastases, but was a false positive in the setting of a recent stroke. Increased PSMA uptake has been reported in subacute infarcts and primary and secondary brain tumors. Careful history and comparison with prior imaging are vital to avoid false-positive diagnosis in such patients.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.