脉络丛癌 (CPC) 是一种罕见的恶性脑肿瘤，主要影响 2 岁以下的儿童。这些肿瘤起源于脉络丛上皮，是脉络丛肿瘤的一个亚型，占小儿脑肿瘤的1%-4%。尽管 CPC 术后复发率通常很高，但由于缺乏支持放疗或化疗等辅助治疗方案有效性的临床数据，标准治疗方法仍然是肿瘤的全切除 (GTR)。A 16-一名 1 岁女性，有复发性颅脑 CPC 病史，对手术和放疗有抵抗力，在切除后接受射波刀立体定向放射外科 (SRS) 治疗。该程序成功维持了当地疾病控制 41 个月；然而，随后复发，最终导致患者死亡。CPC 治疗仍然具有挑战性。 SRS 可以用作手术的可行辅助手段，这仍然是黄金标准，尽管对于非手术候选人或无法实现 GTR 时也可以考虑 SRS。尽管如此，开展更多研究来探索放射外科的不同方法至关重要，包括其作为主要治疗方式的作用以及与手术、放疗或化疗相结合的作用。 https://thejns.org/doi/10.3171/CASE23748。

Choroid plexus carcinomas (CPCs) are rare malignant brain tumors primarily affecting children younger than 2 years old. These tumors originate from the choroid plexus epithelium and are a subtype of choroid plexus tumors, which account for 1%-4% of pediatric brain tumors. Although CPCs often show a notably high recurrence rate after surgery, the standard treatment approach remains gross-total resection (GTR) of the tumor, given the lack of clinical data supporting the effectiveness of adjunct treatment options such as radiotherapy or chemotherapy.A 16-year-old female with a history of a recurrent cranial CPC resistant to surgery and radiotherapy was treated with CyberKnife stereotactic radiosurgery (SRS), following resection. The procedures successfully maintained local disease control for 41 months; however, there was a subsequent recurrence, ultimately leading to the death of the patient.CPC treatment remains challenging. SRS can be used as a viable adjunct to surgery, which remains the gold standard, although it can also be considered for nonsurgical candidates or when GTR cannot be achieved. Nevertheless, it is crucial to conduct additional research to explore diverse approaches for radiosurgery, including its role as the primary treatment modality versus its combination with surgery, radiotherapy, or chemotherapy. https://thejns.org/doi/10.3171/CASE23748.