本研究旨在将体力活动和久坐生活方式与银屑病关节炎 (PsA) 患者队列的临床、生物学、功能和共病参数联系起来。对 232 名 PsA 患者进行了一项横断面研究。使用国际体力活动问卷（IPAQ）问卷获得体力活动和久坐生活方式。测量的人口统计学、临床和生物学变量包括年龄、银屑病关节炎诊断后的时间、吸烟、使用的治疗类型、临床形式、附着点炎、指趾炎（当前或过去）、疲劳、肿瘤坏死因子（TNF）-α和白细胞介素 6 (IL-6)。使用外周形式的银屑病关节炎疾病活动指数（DAPSA）和健康评估问卷（HAQ）测量活动和功能，同时测量强直性脊柱炎疾病活动评分（ASDAS-PCR）和巴斯强直性脊柱炎功能指数（BASFI）以轴向形式。使用银屑病关节炎疾病影响 (PsAID) 调查问卷评估疾病影响。除了合并症之外，还评估了肥胖、焦虑、抑郁 [医院焦虑和抑郁量表 (HADS)] 和睡眠质量 [失眠严重程度指数 (ISI)]。平均年龄为 54.6 (SD: 11.4) 岁，其中 54.3% 为男性。共有25.6%的患者久坐不动。体力活动和久坐生活方式与疲劳、活动、功能和疾病影响呈负相关。在合并症中，它们与焦虑、抑郁和失眠相关。此外，体力活动与肥胖呈负相关。线性回归分析发现，体力活动与体重指数（BMI）相关，β系数为-0.1（p< 0.04；95%CI：-194.1--4.5），R2值为0.11。在逻辑回归分析中，发现久坐的生活方式与疼痛相关，比值比 (OR) 为 1.5（p< 0.001；95%CI：1.1-1.8），R2 Nagelkerke 值为 0.36。患者久坐。缺乏身体活动与较差的临床活动、功能、疾病影响和合并症的存在相关。版权所有 © 2024 Toledano、Chacón、Compán、Gómez-Lechón、Hidalgo、Ibañez、Márquez 和 Montilla。

This study aimed to relate physical activity and a sedentary lifestyle to clinical, biological, functional, and comorbid parameters in a cohort of patients with psoriatic arthritis (PsA).A cross-sectional study was conducted with 232 PsA patients. Physical activity and sedentary lifestyle were obtained using the International Physical Activity Questionnaire (IPAQ) questionnaire. The demographic, clinical, and biological variables measured were age, time since PsA diagnosis, smoking, type of treatment used, clinical form, presence of enthesitis, dactylitis (present or past), fatigue, tumor necrosis factor (TNF)-alpha, and interleukin 6 (IL-6). Activity and functionality were measured using the Disease Activity Index for Psoriatic Arthritis (DAPSA) and Health Assessment Questionnaire (HAQ) in peripheral forms, while the Ankylosing Spondylitis Disease Activity Score (ASDAS-PCR) and Bath Ankylosing Spondylitis Functional Index (BASFI) were measured in axial forms. Disease impact was assessed using the Psoriatic Arthritis Impact of Disease (PsAID) questionnaire. Alongside comorbidities, obesity, anxiety, depression [Hospital Anxiety and Depression Scale (HADS)], and sleep quality [Insomnia Severity Index (ISI)] were assessed.The mean age was 54.6 (SD: 11.4) years, with 54.3% being male. A total of 25.6% of patients were sedentary. Physical activity and sedentary lifestyle were inversely correlated with fatigue, activity, functionality, and disease impact. Within comorbidities, they correlated with anxiety, depression, and insomnia. In addition, physical activity was inversely correlated with obesity. In linear regression analysis, physical activity was found to be related to body mass index (BMI) with a ß coefficient of -0.1 (p < 0.04; 95%CI: -194.1--4.5), and an R2 value of 0.11. In logistic regression analysis, a sedentary lifestyle was found to be related to pain, with an odds ratio (OR) of 1.5 (p < 0.001; 95%CI:1.1-1.8) and an R2 Nagelkerke value of 0.36.A quarter of the patients were sedentary. Lack of physical activity correlated with worse parameters of clinical activity, functionality, disease impact, and the presence of comorbidities.Copyright © 2024 Toledano, Chacón, Compán, Gómez-Lechón, Hidalgo, Ibañez, Márquez and Montilla.