癌症诊断后，疲劳、失眠和睡眠障碍很常见，对生活质量和功能产生负面影响。这篇叙述性综述综合了癌症幸存者癌症相关疲劳、失眠和睡眠障碍的生活方式和综合肿瘤学干预措施的证据。有强有力的证据支持有氧运动和力量运动可以缓解癌症相关的疲劳。瑜伽、按摩疗法、针灸、太极拳和气功也可推荐用于治疗与癌症相关的疲劳。关于瑜伽、针灸和按摩疗法治疗癌症睡眠障碍的证据好坏参半，而运动似乎有一定的积极作用。对于癌症相关的疲劳或失眠和癌症后其他睡眠障碍的营养补充剂或饮食干预措施没有足够的证据。除了减轻与癌症相关的疲劳和失眠相关的症状外，综合肿瘤学和生活方式干预措施还有可能产生多种其他益处，例如改善疼痛和更年期症状等症状。需要对干预措施进行精心设计的随机对照试验，特别是在饮食和营养补充剂领域，以及对已有证据支持的干预措施进行实施研究。版权所有 © 2024 作者。由 Elsevier B.V. 出版。保留所有权利。

Fatigue, insomnia and sleep disturbances are common after cancer diagnosis, and have a negative impact on quality of life and function. This narrative review synthesised evidence on lifestyle and integrative oncology interventions for cancer-related fatigue, insomnia and sleep disturbances in cancer survivors. There is strong evidence in support of aerobic and strength exercise for the relief of cancer-related fatigue. Yoga, massage therapy, acupuncture, Tai Chi and qigong can also be recommended for cancer-related fatigue. The evidence on yoga, acupuncture and massage therapy for sleep disturbances in cancer is mixed, while exercise appears to have a modest favourable effect. There is insufficient evidence on nutrient supplements or dietary interventions for cancer-related fatigue or insomnia and other sleep disturbances after cancer. Beyond alleviating cancer-related fatigue and insomnia-related symptoms, integrative oncology and lifestyle interventions have potential to effect multiple other benefits, such as improvement in symptoms such as pain and menopausal symptoms. There is a need for well-designed randomised controlled trials of interventions, particularly in the areas of diet and nutrient supplements, and for implementation studies of interventions already supported by evidence.Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.