撒下更广泛的网：EV 转录组学在多分析物液体活检中的临床潜力。
Casting a wider net: The clinical potential of EV transcriptomics in multi-analyte liquid biopsy.
发表日期：2024 Jul 08
作者：
Yari Ciani, Caterina Nardella, Francesca Demichelis
来源：
CANCER CELL
摘要：
癌细胞将游离 DNA (cfDNA) 和细胞外囊泡 (EV) 释放到血流中，从而实现疾病的无创监测。在本期《癌细胞》中，Casanova-Salas 等人。分析接受雄激素受体信号抑制剂和紫杉烷治疗的前列腺癌纵向队列中的 cfDNA、EV-DNA 和 EV-RNA，识别反映肿瘤适应过程的信号。版权所有 © 2024 Elsevier Inc. 保留所有权利。
Cancer cells release cell-free DNA (cfDNA) and extracellular vesicles (EVs) into the bloodstream, allowing disease non-invasive monitoring. In this issue of Cancer Cell, Casanova-Salas et al. analyze cfDNA, EV-DNA, and EV-RNA in prostate cancer longitudinal cohorts treated with androgen receptor signaling inhibitors and taxanes, identifying signals reflecting tumor adaptation processes.Copyright © 2024 Elsevier Inc. All rights reserved.