HPV 是导致大多数宫颈癌、口咽癌、肛门癌、阴道癌和外阴癌的原因。 HPV 疫苗降低了宫颈癌的发病率，但只有 49% 的德克萨斯州青少年开始接种疫苗。德克萨斯州的 HPV 疫苗接种率差异很大。我们利用地理空间分析来识别疫苗接种率高低的区域，并探讨社区特征的差异。利用 Anselin 的 Local Moran's I 统计数据，我们对 2017 年至 2021 年德克萨斯州青少年 HPV 疫苗接种覆盖率的热点和冷点进行了生态分析。 ，我们利用儿童机会指数 (COI) 和美国社区调查的数据，利用曼-惠特尼 U 检验来比较热点地区和冷点的疫苗接种覆盖率的社区特征。在德克萨斯州，有 64 个持续的疫苗接种覆盖率热点和 55 个持续的疫苗接种覆盖率热点地区和 55 个地区。持续的疫苗接种覆盖冷点。与疫苗覆盖冷点相比，持续的疫苗接种覆盖率热点地区的特点是邮政编码 COI 分数较低、西班牙裔居民比例较高、贫困率较高以及每平方英里人口较少。我们发现，男性青少年疫苗覆盖率的空间聚类模式比女性青少年疫苗覆盖率的空间聚类模式更明显。在德克萨斯州，HPV 疫苗接种覆盖率因社区收入水平而异，收入较低的地区获得更高的成功率。值得注意的是，疫苗接种覆盖率也存在性别差异，特别是在男性青少年中。这些知识可以帮助倡导者定制他们的外展计划，以解决这些差异。版权所有 © 2024 Ramphul、Zamorano、Upadhyay、Desai 和 Bauer。

HPV is responsible for most cervical, oropharyngeal, anal, vaginal, and vulvar cancers. The HPV vaccine has decreased cervical cancer incidence, but only 49% of Texas adolescents have initiated the vaccine. Texas shows great variation in HPV vaccination rates. We used geospatial analysis to identify areas with high and low vaccination rates and explored differences in neighborhood characteristics.Using Anselin's Local Moran's I statistic, we conducted an ecological analysis of hot and cold spots of adolescent HPV vaccination coverage in Texas from 2017 to 2021. Next, we utilized a Mann-Whitney U test to compare neighborhood characteristics of vaccination coverage in hot spots versus cold spots, leveraging data from the Child Opportunity Index (COI) and American Community Survey.In Texas, there are 64 persistent vaccination coverage hotspots and 55 persistent vaccination coverage cold spots. The persistent vaccination coverage hot spots are characterized by ZIP codes with lower COI scores, higher percentages of Hispanic residents, higher poverty rates, and smaller populations per square mile compared to vaccine coverage cold spots. We found a more pronounced spatial clustering pattern for male adolescent vaccine coverage than we did for female adolescent vaccine coverage.In Texas, HPV vaccination coverage rates differ depending on the community's income level, with lower-income areas achieving higher success rates. Notably, there are also gender-based discrepancies in vaccination coverage rates, particularly among male adolescents. This knowledge can aid advocates in customizing their outreach initiatives to address these disparities.Copyright © 2024 Ramphul, Zamorano, Upadhyay, Desai and Bauer.