心脏肿瘤学健康的社会决定因素:克服护理差异的多层次策略:JACC:心脏肿瘤学最先进的评论。
Social Determinants of Health in Cardio-Oncology: Multi-Level Strategies to Overcome Disparities in Care: JACC: CardioOncology State-of-the-Art Review.
发表日期:2024 Jun
作者:
Foster Osei Baah, Sonal Sharda, Kimberly Davidow, Sadhana Jackson, Daphney Kernizan, Joshua A Jacobs, Yvonne Baumer, Corinna L Schultz, Carissa M Baker-Smith, Tiffany M Powell-Wiley
来源:
Epigenetics & Chromatin
摘要:
满足更公平的心脏肿瘤护理需求需要关注心脏肿瘤疾病预防和结果方面现有的差异。这对于那些受不良健康社会决定因素(SDOH)影响的人来说尤其重要。 SDOH、癌症诊断以及与肿瘤治疗相关的心脏毒性结果之间错综复杂的关系受到社会政治、经济和文化因素的影响。此外,细胞信号传导机制和基因表达的表观遗传效应将不利的 SDOH 与癌症和肿瘤治疗的 CVD 相关并发症联系起来。为了缩小这些差距,需要采取多方面的战略,包括关注医疗保健的获取、政策和社区参与,以改善疾病筛查和管理。跨学科团队还必须促进文化谦逊和能力,并利用新的健康技术促进合作,解决不良 SDOH 对心脏肿瘤结果的影响。© 2024 作者。
Addressing the need for more equitable cardio-oncology care requires attention to existing disparities in cardio-oncologic disease prevention and outcomes. This is particularly important among those affected by adverse social determinants of health (SDOH). The intricate relationship of SDOH, cancer diagnosis, and outcomes from cardiotoxicities associated with oncologic therapies is influenced by sociopolitical, economic, and cultural factors. Furthermore, mechanisms in cell signaling and epigenetic effects on gene expression link adverse SDOH to cancer and the CVD-related complications of oncologic therapies. To mitigate these disparities, a multifaceted strategy is needed that includes attention to health care access, policy, and community engagement for improved disease screening and management. Interdisciplinary teams must also promote cultural humility and competency and leverage new health technology to foster collaboration in addressing the impact of adverse SDOH in cardio-oncologic outcomes.© 2024 The Authors.