心脏肿瘤学中的空气污染和揭示环境关系:JACC:心脏肿瘤学最先进的评论。
Air Pollution in Cardio-Oncology and Unraveling the Environmental Nexus: JACC: CardioOncology State-of-the-Art Review.
发表日期:2024 Jun
作者:
Wenqiang Zhu, Sadeer G Al-Kindi, Sanjay Rajagopalan, Xiaoquan Rao
来源:
Environmental Technology & Innovation
摘要:
尽管癌症治疗的最新进展延长了癌症患者的寿命,但也带来了新的挑战,包括由先前存在的危险因素或癌症治疗引起的心血管疾病等慢性健康问题。因此,心血管疾病已成为癌症患者非癌症相关死亡的主要原因,推动了心脏肿瘤学领域的快速发展。环境因素,特别是空气污染,在很大程度上导致与心血管疾病和特定癌症(例如肺癌)相关的死亡。尽管有这些统计数据,但在患者护理和研究中,心脏肿瘤学背景下空气污染对健康的影响在很大程度上被忽视了。值得注意的是,空气污染的影响在不同地理区域和个人之间存在很大差异,导致不同的暴露后果。本综述旨在巩固将空气污染与心脏肿瘤学联系起来的流行病学和临床前证据,同时探讨相关的健康差异和环境正义问题。© 2024 作者。
Although recent advancements in cancer therapies have extended the lifespan of patients with cancer, they have also introduced new challenges, including chronic health issues such as cardiovascular disease arising from pre-existing risk factors or cancer therapies. Consequently, cardiovascular disease has become a leading cause of non-cancer-related death among cancer patients, driving the rapid evolution of the cardio-oncology field. Environmental factors, particularly air pollution, significantly contribute to deaths associated with cardiovascular disease and specific cancers, such as lung cancer. Despite these statistics, the health impact of air pollution in the context of cardio-oncology has been largely overlooked in patient care and research. Notably, the impact of air pollution varies widely across geographic areas and among individuals, leading to diverse exposure consequences. This review aims to consolidate epidemiologic and preclinical evidence linking air pollution to cardio-oncology while also exploring associated health disparities and environmental justice issues.© 2024 The Authors.