研究动态
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黑人乳腺癌幸存者的社区原型和心血管健康。

Neighborhood Archetypes and Cardiovascular Health in Black Breast Cancer Survivors.

发表日期:2024 Jun
作者: Carola T Sánchez-Díaz, Riddhi A Babel, Hari S Iyer, Noreen Goldman, Nur Zeinomar, Andrew G Rundle, Coral O Omene, Karen S Pawlish, Christine B Ambrosone, Kitaw Demissie, Chi-Chen Hong, Gina S Lovasi, Elisa V Bandera, Bo Qin
来源: JACC: CardioOncology

摘要:

维持心血管健康 (CVH) 对于乳腺癌 (BC) 幸存者至关重要,特别是考虑到癌症治疗的潜在心脏毒性作用。 BC 黑人幸存者中的不良 CVH 可能受到各种地区级健康社会决定因素的影响,但该人群中 CVH 的社区原型的影响仍未得到充分研究。本研究旨在描述 BC 黑人幸存者在诊断和评估时居住的社区原型的特征她们与 CVH 之间的关系。我们在女性健康圈随访研究中评估了 2012 年至 2017 年间诊断的 713 名参与者在诊断后 24 个月的 CVH,这是一项针对新泽西州黑人 BC 幸存者的基于人群的研究。通过基于 16 个社会和建筑环境特征的潜在类别分析确定的邻里原型被分为三分位数。使用多级 Logistic 回归估计邻域原型和 CVH 评分之间的关​​联。CVH 评分按连续变量进行分类(低、中和最佳)评估。平均而言,BC 省黑人幸存者仅获得最佳 CVH 推荐分数的一半。在 4 种确定的原型中,文化背景以黑人和西班牙裔/混合土地利用为主的女性表现出最低的 CVH 得分。与此原型相比,文化多元化/混合土地利用原型中的黑人 BC 幸存者拥有最佳 CVH 的可能性几乎是其 3 倍(相对风险比:2.92;95% CI:1.58-5.40),并且在年轻人中观察到更强的相关性或绝经前妇女。对于其他 2 个建筑环境特征较少的原型,没有发现显着的 CVH 差异。社区原型,整合了社会和建筑环境因素,可能代表了在 BC 幸存者中促进 CVH 的关键目标。© 2024 作者。
Maintaining cardiovascular health (CVH) is critical for breast cancer (BC) survivors, particularly given the potential cardiotoxic effects of cancer treatments. Poor CVH among Black BC survivors may be influenced by various area-level social determinants of health, yet the impact of neighborhood archetypes in CVH among this population remains understudied.This study aimed to characterize the neighborhood archetypes where Black BC survivors resided at diagnosis and evaluate their associations with CVH.We assessed CVH 24 months post-diagnosis in 713 participants diagnosed between 2012 and 2017 in the Women's Circle of Health Follow-Up Study, a population-based study of Black BC survivors in New Jersey. Neighborhood archetypes, identified via latent class analysis based on 16 social and built environment features, were categorized into tertiles. Associations between neighborhood archetypes and CVH scores were estimated using polytomous logistic regression.CVH scores were assessed categorically (low, moderate, and optimal) and as continuous variables. On average, Black BC survivors achieved only half of the recommended score for optimal CVH. Among the 4 identified archetypes, women in the Mostly Culturally Black and Hispanic/Mixed Land Use archetype showed the lowest CVH scores. Compared to this archetype, Black BC survivors in the Culturally Diverse/Mixed Land Use archetype were nearly 3 times as likely to have optimal CVH (relative risk ratio: 2.92; 95% CI: 1.58-5.40), with a stronger association observed in younger or premenopausal women. No significant CVH differences were noted for the other 2 archetypes with fewer built environment features.Neighborhood archetypes, integrating social and built environment factors, may represent crucial targets for promoting CVH among BC survivors.© 2024 The Authors.