旨在评估健康社会决定因素 (SDOH) 对非​​裔美国人 (AA)/黑人和西班牙裔卵巢癌幸存者感知健康和福祉的影响。利用由美国国立卫生研究院 2017 年 5 月至 2023 年 9 月的“我们所有人研究计划”。虽然 1250 名患有卵巢癌的登记参与者符合纳入标准，但 414 人 (33%) 完成了 SDOH 调查：29 人 (7%) AA/黑人，33 人 (8%) ) 西班牙裔，以及 352 (85%) 白人。在序数逻辑回归模型中，SDOH 邻域特征得分每增加一个单位，总体健康状况不佳的几率就会降低 0.96 倍。 SDOH日常歧视得分每增加一个单位，对总体健康、总体心理健康、社会满意度的感知较差的几率分别下降0.95、0.94和0.93倍。 SDOH 食品和住房安全得分每提高一个单位，总体健康状况不佳的几率就会降低 0.57 倍。与白人卵巢癌幸存者相比，AA/黑人和西班牙裔卵巢癌幸存者即使在调整这些 SDOH 时，对总体健康、总体心理健康和社会满意度的感知也明显更差。不利的 SDOH 条件会对整体感知产生负面影响的健康。这些发现表明，医疗保健专业人员和科学家迫切需要与当地社区合作，设计可行且富有想象力的干预措施，以公平的方式克服癌症护理差异。版权所有 © 2024 作者。由爱思唯尔公司出版。保留所有权利。

To evaluate the influences of social determinants of health (SDOH) on perceived health and well-being among African American (AA)/Black and Hispanic ovarian cancer survivors.A cross-sectional study was conducted using overall health and SDOH survey data collected by the National Institutes of Health All of Us Research Program from May 2017 to September 2023.While 1250 enrolled participants with ovarian cancer met the inclusion criteria, 414 (33%) completed SDOH surveys: 29 (7%) AA/Black, 33 (8%) Hispanic, and 352 (85%) White. In the ordinal logistic regression models, for every unit increase in the SDOH neighborhood characteristics score, the odds of having a poor perception of general health decreased by 0.96 times. For every unit increase in the SDOH day-to-day discrimination score, the odds of having a poor perception of general health, general mental health, social satisfaction decreased by 0.95, 0.94 and 0.93 times respectively. For every unit increase in the SDOH food and housing security score, the odds of having a poor perception of general health decreased by 0.57 times. Compared to White ovarian cancer survivors, AA/Black and Hispanic ovarian cancer survivors were significantly more likely to have a poor perception of general health, general mental health, and social satisfaction even when adjusting for these SDOH.Unfavorable SDOH conditions negatively influence the overall perception of health. These findings signal an urgency for healthcare professionals and scientists to partner together with local communities in designing feasible and imaginative interventions to overcome cancer care disparities in an equitable manner.Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.