研究动态
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腹股沟区淋巴结切除术的并发症和不良事件:全球专家共识。

Complications and adverse events in lymphadenectomy of the inguinal area: worldwide expert consensus.

发表日期:2024 Jul 02
作者: René Sotelo, Aref S Sayegh, Luis G Medina, Laura C Perez, Anibal La Riva, Michael B Eppler, José Gaona, Marcos Tobias-Machado, Philippe E Spiess, Curtis A Pettaway, Antonio Carlos Lima Pompeo, Pablo Aloisio Lima Mattos, Timothy G Wilson, Gustavo M Villoldo, Eric Chung, Aldo Samaniego, Antonio Augusto Ornellas, Vladimir Pinheiro, Eder S Brazão, David Subira-Rios, Leandro Koifman, Stênio de Cassio Zequi, Humberto M Pontillo Z, José de Ribamar Rodrigues Calixto, Rafael Campos Silva, B Mark Smithers, Simone Garzon, Oliver Haase, Antonio Sommariva, Robert Fruscio, Francisco Martins, Pedro S de Oliveira, Giovanni Battista Levi Sandri, Marco Clementi, Juan Astigueta, Islam H Metwally, Rasiah Bharathan, Tarun Jindal, Yasuhiro Nakamura, Hisham Abdel Mageed, Sakthiushadevi Jeevarajan, Ramón Rodriguez Lay, Herney Andrés García-Perdomo, Omaira Rodríguez González, Saum Ghodoussipour, Inderbir Gill, Giovanni E Cacciamani
来源: BJS Open

摘要:

腹股沟淋巴结清扫术在黑色素瘤、阴茎癌和外阴癌的治疗中发挥着重要作用。腹股沟淋巴结清扫与各种术中和术后并发症相关,其分类和报告存在显着异质性。这种标准化的缺乏对研究和报告腹股沟淋巴结清扫结果的努力提出了挑战。本研究的目的是通过创建腹股沟区淋巴结清扫术 (CALI) 组的并发症和不良事件的全球协作,设计一个系统来标准化腹股沟淋巴结清扫术围手术期并发症的分类和报告。改进的 3 轮德尔菲共识方法对全球黑色素瘤、阴茎癌和外阴癌腹股沟淋巴结清扫术专家组进行了调查。专家组包括普通外科医生、泌尿科医生和肿瘤科医生(妇科和外科)。该调查评估了专家对腹股沟淋巴结清扫术围手术期并发症的共识。小组间的一致性和一致性以总体百分比一致性和 Cronbach α 进行评估。 纳入了 47 名经验丰富的顾问:26 名 (55.3%) 泌尿科医生、11 名 (23.4%) 肿瘤科医生、6 名 (12.8%) 普通外科医生和 4 名 (8.5%) 外科医生。 %) 妇科肿瘤学家。根据他们的专业知识,分别有 31 名(66%)、10 名(21.3%)和 22 名(46.8%)参与者使用腹股沟淋巴结清扫术治疗阴茎癌、外阴癌和黑色素瘤; 89.4%(47 人中的 42 人)同意定义并将其纳入腹股沟淋巴结清扫术中并发症组,而 93.6%(47 人中的 44 人)同意术后并发症应分为五个宏观类别。报告黑色素瘤、外阴癌和阴茎癌腹股沟淋巴结清扫并发症的最终标准化分类系统获得了一致同意(100%,37个中的37个)。腹股沟区域淋巴结切除术的并发症和不良事件分类系统已经开发出来作为标准化腹股沟淋巴结清扫治疗黑色素瘤、外阴癌和阴茎癌期间并发症评估和报告的工具。© 作者 2024。由牛津大学出版社代表 BJS Foundation Ltd 出版。
Inguinal lymph node dissection plays an important role in the management of melanoma, penile and vulval cancer. Inguinal lymph node dissection is associated with various intraoperative and postoperative complications with significant heterogeneity in classification and reporting. This lack of standardization challenges efforts to study and report inguinal lymph node dissection outcomes. The aim of this study was to devise a system to standardize the classification and reporting of inguinal lymph node dissection perioperative complications by creating a worldwide collaborative, the complications and adverse events in lymphadenectomy of the inguinal area (CALI) group.A modified 3-round Delphi consensus approach surveyed a worldwide group of experts in inguinal lymph node dissection for melanoma, penile and vulval cancer. The group of experts included general surgeons, urologists and oncologists (gynaecological and surgical). The survey assessed expert agreement on inguinal lymph node dissection perioperative complications. Panel interrater agreement and consistency were assessed as the overall percentage agreement and Cronbach's α.Forty-seven experienced consultants were enrolled: 26 (55.3%) urologists, 11 (23.4%) surgical oncologists, 6 (12.8%) general surgeons and 4 (8.5%) gynaecology oncologists. Based on their expertise, 31 (66%), 10 (21.3%) and 22 (46.8%) of the participants treat penile cancer, vulval cancer and melanoma using inguinal lymph node dissection respectively; 89.4% (42 of 47) agreed with the definitions and inclusion as part of the inguinal lymph node dissection intraoperative complication group, while 93.6% (44 of 47) agreed that postoperative complications should be subclassified into five macrocategories. Unanimous agreement (100%, 37 of 37) was achieved with the final standardized classification system for reporting inguinal lymph node dissection complications in melanoma, vulval cancer and penile cancer.The complications and adverse events in lymphadenectomy of the inguinal area classification system has been developed as a tool to standardize the assessment and reporting of complications during inguinal lymph node dissection for the treatment of melanoma, vulval and penile cancer.© The Author(s) 2024. Published by Oxford University Press on behalf of BJS Foundation Ltd.