在我们的研究中，我们的目的是描述成年儿童癌症幸存者 (ACCS) 的特征，评估他们的健康问题，衡量与健康相关的生活质量 (HRQOL) 并评估就诊满意度。使用临床就诊和问卷调查数据进行前瞻性队列研究。跨学科随访根据儿童肿瘤学组的长期随访 (LTFU) 指南，并由两家瑞士医院的内科医生监督的 ACCS 计划。2017 年 4 月至 2022 年 1 月期间到我们的 LTFU 诊所就诊的 ACCS 符合资格。我们记录了病史，目前的健康状况，并使用 Short Form-36 V.2 评估 HRQOL，并将其与瑞士普通人群 (SGP) 规范进行比较（T 平均值 = 50，SD = 10；年龄分层）。访视后 3 个月，发放反馈问卷。 在 102 名 ACCS 中（平均年龄：32 岁（范围：18-62 岁），68% 女性），43 名之前没有随访（36 名 ACCS>28 岁，7 名 ACCS ≤28岁）。值得注意的是，94% 的人存在健康问题，平均影响 6.1 (SD=3.3) 个器官系统。 ACCS>28 岁的 HRQOL 低于 SGP>28 岁（身体：44.8 (SD=11.65) vs 49.3 (SD=10.29)，p=0.016；精神：44.4 (SD=13.78) vs 50.53 (SD=9.92) ，p=0.004）。较年长的 ACCS（>28 岁）报告的身体素质（44.8 vs 50.1 (SD=9.30)，p=0.017）和精神 HRQOL（44.4 vs 50.3 (SD=7.20)，p=0.009）低于年轻的 ACCS。大多数受访者对咨询的满意度很高，超过 90%。与 SGP 相比，参加 LTFU 诊所的 ACCS 面临着影响多​​个器官系统的各种健康问题，并且 HRQOL 较低。因此，内科医生主导的 LTFU 诊所对于优化后续护理至关重要。© 作者（或其雇主）2024。CC BY-NC 允许重复使用。不得商业再利用。请参阅权利和权限。由英国医学杂志出版。

In our study, we aimed to characterise adult childhood cancer survivors (ACCS), assess their health issues, gauge health-related quality of life (HRQOL) and evaluate visit satisfaction.Prospective cohort study using data from clinical visits and questionnaires.Interdisciplinary follow-up programme for ACCS based on the long-term follow-up (LTFU) guidelines of the Children's Oncology Group and overseen by internists in two Swiss hospitals.ACCS attending our LTFU clinics between April 2017 and January 2022 were eligible.We documented medical history, current health status and assessed HRQOL using Short Form-36 V.2, comparing it with Swiss general population (SGP) norms (T mean=50, SD=10; age stratified). 3 months post visit, a feedback questionnaire was distributed.Among 102 ACCS (mean age: 32 years (range: 18-62 years), 68% women), 43 had no prior follow-up (36 ACCS>28 years, 7 ACCS≤28 years). A notable 94% had health issues, affecting an average of 6.1 (SD=3.3) organ systems. HRQOL was lower in ACCS>28 years than the SGP>28 years (physical: 44.8 (SD=11.65) vs 49.3 (SD=10.29), p=0.016; mental: 44.4 (SD=13.78) vs 50.53 (SD=9.92), p=0.004). Older ACCS (>28 years) reported inferior physical (44.8 vs 50.1 (SD=9.30), p=0.017) and mental HRQOL (44.4 vs 50.3 (SD=7.20), p=0.009) than younger ACCS. The majority of respondents reported high levels of satisfaction with the consultation, exceeding 90%.ACCS attending LTFU clinics face diverse health issues impacting multiple organ systems and exhibit lower HRQOL compared with the SGP. Thus, internist-led LTFU clinics are crucial for optimising follow-up care.© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.