研究动态
Articles below are published ahead of final publication in an issue. Please cite articles in the following format: authors, (year), title, journal, DOI.

纳米颗粒在癌症治疗诊断和药物输送中的应用:综合综述。

Nanoparticles in cancer theragnostic and drug delivery: A comprehensive review.

发表日期:2024 Jul 09
作者: Alshayma N Al-Thani, Asma Ghafoor Jan, Mohamed Abbas, Mithra Geetha, Kishor Kumar Sadasivuni
来源: LIFE SCIENCES

摘要:

这篇全面的综述深入分析了纳米技术如何彻底改变癌症治疗诊断学,结合诊断和治疗方法来定制癌症治疗。该研究探讨了不同类型纳米粒子(包括金、氧化铁、二氧化硅、量子点、碳纳米管和脂质体)在癌症治疗中的独特属性、用途和困难。此外,本文还探讨了纳米治疗学的进展,强调其在精确药物管理、光热疗法以及 MRI、CT 和荧光成像等复杂诊断方法中的应用。此外,文章还强调了纳米颗粒能够提高药物的有效性,降低体内的总体毒性,并通过以受控方式释放药物并针对特定区域,为治疗癌症开辟新的可能性。此外,它解决了有关纳米粒子的相容性及其潜在有害影响的担忧,强调了持续研究以改进医疗中使用的纳米治疗方法的重要性。该评论最后概述了纳米技术在预测肿瘤学和定制医学中的潜在未来应用。版权所有 © 2024。由 Elsevier Inc. 出版。
This comprehensive review provides an in-depth analysis of how nanotechnology has revolutionized cancer theragnostic, which combines diagnostic and therapeutic methods to customize cancer treatment. The study examines the unique attributes, uses, and difficulties linked to different types of nanoparticles, including gold, iron oxide, silica, Quantum dots, Carbon nanotubes, and liposomes, in the context of cancer treatment. In addition, the paper examines the progression of nanotheranostics, emphasizing its uses in precise medication administration, photothermal therapy, and sophisticated diagnostic methods such as MRI, CT, and fluorescence imaging. Moreover, the article highlights the capacity of nanoparticles to improve the effectiveness of drugs, reduce the overall toxicity in the body, and open up new possibilities for treating cancer by releasing drugs in a controlled manner and targeting specific areas. Furthermore, it tackles concerns regarding the compatibility of nanoparticles and their potential harmful effects, emphasizing the significance of continuous study to improve nanotherapeutic methods for use in medical treatments. The review finishes by outlining potential future applications of nanotechnology in predictive oncology and customized medicine.Copyright © 2024. Published by Elsevier Inc.