研究动态
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韩国原子弹幸存者群体自我报告发病情况的验证。

Validation of self-reported morbidities of the Korean Atomic Bomb Survivor Cohort.

发表日期:2024 Jun 28
作者: Ansun Jeong, Thi Xuan Mai Tran, Seong-Geun Moon, Mi Kyung Kim, Inah Kim, Yu-Mi Kim, Boyoung Park
来源: Epidemiology and Health

摘要:

本研究旨在评估通过韩国原子弹幸存者队列 (K-ABC) 调查收集的疾病状况的一致性,并与韩国国民健康保险服务 (NHIS) 数据库和韩国中央癌症登记处的医疗索赔记录进行比较。 KCCR)。2020 年至 2022 年间,通过访谈者填写的问卷收集了 1,215 名 K-ABC 参与者的终生医生诊断发病率数据。调查数据与 NHIS 和 KCCR 数据库相关联。包括十一种疾病进行验证。我们评估了以下指标:敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)、准确性、曲线下面积(AUC)和kappa系数。平均(标准差)年龄为62.1( 18.7)岁,42.6%的参与者年龄≥70岁。高血压和白内障的患病率最高(分别为 33.8% 和 28.8%)。高血压、糖尿病和癌症表现出较高的敏感性(>0.8)和特异性(>0.9),而糖尿病、癌症、心肌梗塞、心绞痛和哮喘则表现出较高的准确性(>0.9)。相反,关节炎、过敏性鼻炎和哮喘表现出较低的敏感性(<0.4)和卡帕值(<0.3)。在年龄≥70岁的参与者中,除关节炎、过敏性鼻炎和哮喘之外的所有疾病的kappa值均≥0.4。初步分析的结果显示,调查与NHIS/KCCR数据库之间的一致性相对较高,尤其是高血压、糖尿病和癌症。我们的研究结果表明,通过该队列中的问卷调查收集的发病信息对于年轻人和老年人都有效。
This study aimed to evaluate the agreement of disease status collected through a survey of the Korean Atomic Bomb Survivor Cohort (K-ABC), compared with medical claim records from the Korean National Health Insurance Service (NHIS) database and the Korean Central Cancer Registry (KCCR).Data on the lifetime physician-diagnosed morbidities of 1,215 K-ABC participants were collected through an interviewer-administered questionnaire between 2020 and 2022. Survey data were linked to the NHIS and KCCR databases. Eleven diseases were included for validation. We evaluated the following indicators: sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, the area under the curve (AUC), and the kappa coefficient.The mean (standard deviation) age was 62.1 (18.7) years, and 42.6% of the participants were aged ≥70 years. Hypertension and cataracts showed the highest prevalence rates (33.8% and 28.8%, respectively). Hypertension, diabetes, and cancer demonstrated high sensitivity (>0.8) and specificity (>0.9), whereas diabetes, cancer, myocardial infarction, angina pectoris, and asthma exhibited high accuracy (>0.9). In contrast, arthritis, allergic rhinitis, and asthma showed low sensitivity (<0.4) and kappa values (<0.3). In the participants aged ≥70 years, the kappa value was ≥0.4 for all diseases except arthritis, allergic rhinitis, and asthma.The results from this initial analysis showed relatively high agreement between the survey and NHIS/KCCR databases, especially for hypertension, diabetes, and cancer. Our findings suggest that the information on morbidities collected through the questionnaires in this cohort was valid for both younger and older individuals.