本研究通过对潜在类别及其影响因素的分析，调查了医护人员对抗肿瘤药物（AD）职业防护的知识、态度和实践水平。采用便利抽样法，于2023年4月至2023年8月期间抽取华南地区7家医院的医护人员，采用基于文献分析、头脑风暴法和德尔菲法的调查问卷，调查医护人员的知识、行为和态度。 AD 进行适当的职业保护干预，然后进行潜在类别分析。通过单因素分析和多元逻辑回归确定了影响潜在类别的因素。共有 322 名来自使用 AD 的部门的医护人员接受了调查。 AD职业防护相关知识得分为31.95±7.38。态度得分为21.08±2.729，实践得分为36.54±9.485。总分89.57±15.497。根据与AD职业防护措施相关的知识、态度和实践，将医护人员分为4个潜在类别。 4类医护人员在职称、婚姻状况、教育背景和AD暴露频率方面存在显着差异（P < .05）。从事ADs工作的医护人员的知识、态度和实践水平可分为4个潜在等级。尽管医护人员对 AD 相关危害的认识有所提高，对防护的态度也有所提高，但他们对职业防护措施的了解和实施情况却很差。版权所有 © 2024 作者。由 Wolters Kluwer Health, Inc. 出版

The study investigated the health care workers' knowledge, attitudes, and practice levels regarding occupational protection against antineoplastic drugs (ADs) via analysis of latent classes and their influencing factors. A convenience sampling method was used to select healthcare workers from 7 hospitals in southern China between April and August 2023. A questionnaire based on literature analysis, brainstorming, and Delphi method was used to investigate the knowledge, practice, and attitudes of healthcare workers exposed to ADs for appropriate occupational protection intervention, followed by latent class analysis. The factors influencing latent classes were identified via single-factor analysis and multiple logistic regression. A total of 322 healthcare workers from departments using ADs were surveyed. The knowledge score associated with occupational protection against ADs was 31.95 ± 7.38. The attitude score was 21.08 ± 2.729, while the practice score was 36.54 ± 9.485. The overall score was 89.57 ± 15.497. The healthcare workers were divided into 4 latent classes based on their knowledge, attitude, and practice associated with occupational protection measures against ADs. Healthcare workers in the 4 categories showed significance differences based on professional title, marital status, educational background, and frequency of exposure to ADs (P < .05). The knowledge, attitude, and practice levels of healthcare workers engaged in ADs at work can be divided into 4 latent classes. Despite their increased awareness of the hazards associated with ADs and their attitudes toward protection, the healthcare workers displayed poor knowledge and implementation of occupational protection measures.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.