从一源多物质角度分析中药生姜的药理活性及临床应用
Pharmacological activity and clinical application analysis of traditional Chinese medicine ginger from the perspective of one source and multiple substances.
发表日期:2024 Jul 12
作者:
Cheng Zhang, Anyang Rao, Cui Chen, Yuqing Li, Xiuchi Tan, Jiaxin Long, Xinyue Wang, Junjie Cai, Jiquan Huang, Hua Luo, Chuwen Li, Yuanye Dang
来源:
Chinese Medicine
摘要:
所有类型的生姜都有共同的基本成分,尽管它们在功效和药用方面具有不同的优势和倾向。生姜具有有效刺激体内运动、缓解呕吐、发汗、缓解外在症状的能力。干姜兼具防御与兴奋的特性,能有效提升体内温度,增强阳气。鲜姜比干姜补水,具有温中止痛、止血止泻的功效。干姜热食可散寒,热食可止泻。它在温暖的条件下茁壮成长,并有恢复其温暖性质的倾向。烤姜的水分含量不如干姜,但温中止痛、止血、止泻效果很好。炭化后的姜炭、炒炭具有优良的保温性能,具有温经止血的功效。与新鲜生姜相比,烤姜的效力和传播能力较弱,并且其水分含量也不像干姜那么低。该物质药性温和,有利于体质虚弱患者缓解呕吐。其主要作用于中焦。然而,由于各种中药的基本元素相同,其主要化学成分几乎相同。尤其是生姜,具有一系列药理活性,包括抗氧化、抗炎、抗肿瘤、抗菌和抗凝血特性。但现代药理学研究尚未充分认识生姜的临床药用价值,未能为临床用药提供准确指导。这种情况对当代中医药的发展产生了负面影响。生姜现代化研究是在分析和思考前景的基础上进行的。它以中医理论为基础,融入中医哲学的综合视角。生姜的现代化,必须正确认识“以药识性、同源性、性与功效互表”和“合理运用现代药物研究技术”的理念。通过应用这些原则,我们可以构建一座通向生姜进步的桥梁。© 2024。作者。
All types of ginger have common fundamental components, although they possess distinct strengths and inclinations when it comes to effectiveness and medicinal applications. Fresh ginger possesses the ability to effectively stimulate movement within the body, alleviate the act of vomiting, induce sweating, and provide relief for external syndromes. Dried ginger possesses both defensive and stimulant characteristics, which effectively raise the internal temperature and enhance the Yang energy. Fresh ginger is more hydrating than dried ginger, highly skilled at heating the Middle-jiao, alleviating pain, halting bleeding, and managing diarrhea. Dried ginger possesses the ability to alleviate coldness when consumed in a heated form, as well as to alleviate diarrhea when consumed in a heated form. It thrives in warm conditions and has a tendency to revert back to its warm nature. The moisture content of baked ginger is inferior to that of dried ginger, but it is highly effective in alleviating pain, bleeding, and diarrhea by warming the Middle-jiao. Ginger charcoal and stir-fried charcoal, produced through carbonization, have excellent heat retention properties and are effective in warming meridians and stopping bleeding. The potency and ability to spread of roasted ginger is less intense compared to fresh ginger, and its moisture content is not as low as that of dried ginger. The medicinal characteristics of this substance are gentle, making it beneficial for alleviating vomiting in patients who are physically frail. Its primary mode of action is on the Middle-jiao. Nevertheless, the main chemical compositions of various traditional Chinese medicines are nearly identical due to their shared base element. Ginger, in particular, possesses a range of pharmacological activities including antioxidant, anti-inflammatory, anti-tumor, anti-bacterial, and anticoagulant properties. However, modern pharmacological research has not fully acknowledged the clinical medicinal value of ginger and consequently, fails to provide accurate guidance for clinical medication. This situation has a negative impact on the contemporary advancement of traditional Chinese medicine (TCM). The research on modernizing ginger is conducted by analyzing and considering the prospects. It is based on Traditional Chinese Medicine (TCM) theory and incorporates the comprehensive perspective of TCM philosophy. In order to modernize ginger, it is essential to have a proper knowledge of the concepts of "recognizing nature by efficacy, homology, and mutual expression of nature and efficacy" and "rationally utilizing modern drug research technology". By applying these principles, we can construct a bridge towards the advancement of ginger.© 2024. The Author(s).