Mondia Whitei 是一种原产于撒哈拉以南非洲的芳香植物。这种香料常用于治疗各种疾病，如高血压、糖尿病、勃起功能障碍和早泄。本次审查的目的是提供与非洲人口高度相关的这种植物的植物学、植物化学、药理学和毒理学知识的最新信息。此外，根据先前的实验研究描述了其作用机制。数据来自各种在线数据库，例如 PubMed、Google Scholar、Scopus、Science Direct、Web of Science、Springer link、Taylor and Francis 和 SciFinder。此外，书籍、书籍章节和会议记录也被用作二手资源。使用 PubChem Sketcher 程序绘制植物化合物的化学结构。 M.whitei含有多种植物化合物，包括还原糖、三萜、类固醇、生物​​碱、皂苷、单宁、酚类、氰化氢、类胡萝卜素、草酸盐和植酸盐。此外，从该香料中分离出对苯甲酸对戊基苯酯、(-)-黑麦内酯、5-氯丙烷辛、丙烷辛、2-羟基-4-甲氧基苯甲醛、异香草醛、9-己二烯、2-己烯-1-醇和二十七烷。 M.whitei 具有多种药理功效，包括催情、促生育、促勃起、雄激素、抗氧化剂、抗寄生虫、抗疟、抗菌、抗病毒、抗真菌、抗癫痫、抗炎、镇痛、抗抑郁、止泻、保肝、抗镰刀和抗癌活性。毒理学研究显示LD50超过5000mg/Kg，口服治疗一周后无毒性迹象。这种香料的催情作用是其主要活性之一，并得到大量实验研究的支持。由于怀特氏球菌延迟了球海绵体肌的收缩，因此其催情作用可以通过调节射精的脊髓发生器来介导。这可以证明其在治疗早泄方面的民间传说是合理的。版权所有 © 2023。由 Elsevier B.V. 出版。

Mondia whitei is an aromatic plant native to sub-Saharan Africa. This spice is commonly used in the treatment of various diseases, such as hypertension, diabetes, erectile dysfunction, and premature ejaculation. This review was undertaken to provide updated information on the botanical, phytochemical, pharmacological, and toxicological knowledge of this plant of high relevance to African populations. Moreover, its mechanism of action was described based on previous experimental studies. Data were compiled from various online databases such as PubMed, Google Scholar, Scopus, Science Direct, Web of Science, Springer link, Taylor and Francis, and SciFinder. Additionally, books, book chapters and proceedings were used as secondary sources. The chemical structures of phytocompounds were drawn using PubChem Sketcher program. M. whitei contains various phytocompounds, including reducing sugars, triterpenes, steroids, alkaloids, saponins, tannins, phenolics, hydrogen cyanide, carotenoid, oxalate and phytate. Moreover, para-pentylphenyl-benzoate, (-)-Loliolide, 5-chloropropacin, propacin, 2-hydroxy-4-methoxybenzaldehyde, isovanillin, 9-hexacosene, 2-hexen-1-ol, and heptacosane were isolated from this spice. M. whitei has several pharmacological benefits, including aphrodisiac, pro-fertile, pro-erectile, androgenic, antioxidant, antiparasitic, antimalarial, antibacterial, antiviral, antifungal, antiepileptic, anti-inflammatory, analgesic, antidepressant, antidiarrheal, hepatoprotective, antisickling, and anticancer activities. Toxicological studies showed an LD50 of above 5000 mg/Kg and no signs of toxicity after one week of oral treatment. The aphrodisiac effect of this spice is one of its main activities, supported by numerous experimental studies. Because M. whitei delays contractions of the bulbospongiosus muscles, its aphrodisiac effect could be mediated through the modulation of the spinal generator of ejaculation. This can justify its folkloric use in the treatment of premature ejaculation.Copyright © 2023. Published by Elsevier B.V.