光动力疗法 (PDT) 是一种微创治疗方法，有望对抗癌症和微生物感染。 PDT 靶向肿瘤细胞，同时保护健康组织，减少副作用。它诱导免疫原性细胞死亡，可能刺激抗肿瘤免疫反应并减少癌症复发。在微生物治疗中，PDT可有效对抗细菌、真菌和病毒。 PDT与化疗、放疗、免疫治疗相结合可增强其疗效。然而，肿瘤缺氧、有限的组织渗透和光毒性等挑战需要不断的研究工作来优化 PDT 方案并克服局限性。总体而言，PDT 用途广泛，并不断改进完善的方案，以提高其针对癌症和微生物感染的临床效用。版权所有 © 2024 Elsevier Ltd。保留所有权利。

Photodynamic therapy (PDT) is a minimally invasive treatment showing promise against cancer and microbial infections. PDT targets tumor cells while sparing healthy tissue, reducing side effects. It induces immunogenic cell death, potentially stimulating antitumor immune responses and reducing cancer recurrence. In microbial treatment, PDT effectively combats bacteria, fungi and viruses. Combining PDT with chemotherapy, radiotherapy and immunotherapy enhances its efficacy. However, challenges such as tumor hypoxia, limited tissue penetration and phototoxicity necessitate ongoing research efforts to optimize PDT protocols and overcome limitations. Overall, PDT is versatile and continually advancing with refined protocols to improve its clinical utility against cancer and microbial infections.Copyright © 2024 Elsevier Ltd. All rights reserved.