生物医学工程中出现了环保材料，推动了基于壳聚糖的水凝胶的重大进步。这些水凝胶由于其无毒、生物可降解性、生物相容性、环境友好、经济实惠且易于获取，为传统聚合物提供了一种有前景的绿色替代品。壳聚糖水凝胶以其药物封装、递送能力、生物传感、功能支架和抗菌行为等卓越特性而闻名，处于生物医学研究的前沿。本文探讨了壳聚糖水凝胶的多种应用的制造和改性方法，强调了它们在推进气候中性医疗技术方面的作用。它回顾了壳聚糖水凝胶在癌症诊断、药物输送和伤口护理方面的重大科学进展和趋势。此外，它还解决了当前的挑战和支持循环经济的绿色合成实践，增强了生物医学的可持续性。通过对气候中和管理的最新证据进行深入分析，本综述旨在促进知情决策并促进利用壳聚糖水凝胶技术制定可持续战略。这项全面检查的见解对于指导可持续生物医学解决方案的未来研究和应用至关重要。版权所有 © 2024。由 Elsevier B.V. 出版。

Eco-friendly materials have emerged in biomedical engineering, driving major advances in chitosan-based hydrogels. These hydrogels offer a promising green alternative to conventional polymers due to their non-toxicity, biodegradability, biocompatibility, environmental friendliness, affordability, and easy accessibility. Known for their remarkable properties such as drug encapsulation, delivery capabilities, biosensing, functional scaffolding, and antimicrobial behavior, chitosan hydrogels are at the forefront of biomedical research. This paper explores the fabrication and modification methods of chitosan hydrogels for diverse applications, highlighting their role in advancing climate-neutral healthcare technologies. It reviews significant scientific advancements and trends chitosan hydrogels focusing on cancer diagnosis, drug delivery, and wound care. Additionally, it addresses current challenges and green synthesis practices that support a circular economy, enhancing biomedical sustainability. By providing an in-depth analysis of the latest evidence on climate-neutral management, this review aims to facilitate informed decision-making and foster the development of sustainable strategies leveraging chitosan hydrogel technology. The insights from this comprehensive examination are pivotal for steering future research and applications in sustainable biomedical solutions.Copyright © 2024. Published by Elsevier B.V.