比较腹腔镜或开腹手术治疗FIGO I期上皮性卵巢癌后的肿瘤学结果。回顾性队列研究。某三级医院妇科肿瘤病房。共85例接受腹腔镜分期手术的FIGO I期上皮性卵巢癌患者和206例患者2013年1月1日至2019年12月31日期间在四川大学华西第二医院（中国成都）接受腹腔镜手术或开腹分期手术的患者。在基于倾向评分的匹配之前，剖腹手术组的患病率较高术前 CA125 水平升高（48.5% vs 35.3%，p=.045）且肿瘤 > 15 cm（27.2% vs 5.9%，p < .001）。多变量分析将较高的体重指数与较好的总生存率相关（调整后的 HR 0.83，95%CI 0.70-0.99，p=0.043）。在倾向评分匹配的患者（每组 82 名）中，根据基于年龄、体重指数、CA125 水平、最大肿瘤直径、FIGO 分期、腹部手术史和美国麻醉医师协会等级的倾向评分进行相互匹配，腹腔镜组 (87.1%, 95%CI 79.3-95.7%) 和剖腹手术组 (90.9%, 95%CI 84.7-97.6%, p=.524) 之间的 5 年无进展生存率相似，5 年总生存率也是如此（93.9%，95%CI 88.0-100.0% vs 94.7%，95%CI 89.8-99.9%，p=.900）。无论患者是否匹配，在中位 54.9 个月的随访期间，两组的复发率相似，均为 9-11%。腹腔镜检查或剖腹手术治疗 I 期上皮性卵巢癌的复发率和生存率可能相似。由于腹腔镜手术出血少、恢复快，因此对于合适的患者来说，它可能是剖腹手术的安全、有效的替代方案。版权所有 © 2024。由 Elsevier Inc. 出版。

To compare oncologic outcomes after laparoscopic or laparotomic surgery to treat epithelial ovarian carcinoma in FIGO stage I.Retrospective cohort study.Gynecological cancer ward in a tertiary hospital.A total of 85 patients with FIGO stage I epithelial ovarian carcinoma who underwent laparoscopic staging surgery and 206 who underwent laparotomic staging surgery at West China Second Hospital, Sichuan University (Chengdu, China) between January 1, 2013 and December 31, 2019.laparoscopic surgery or laparotomic staging surgery.Before propensity score-based matching, the laparotomy group showed higher prevalence of preoperative elevated CA125 level (48.5% vs 35.3%, p = .045) and tumors > 15 cm (27.2% vs 5.9%, p < .001). Multivariate analysis associated higher body mass index with better overall survival (adjusted HR 0.83, 95%CI 0.70-0.99, p = .043). Among propensity score-matched patients (82 per group) who were matched to each other according to propensity scoring based on age, body mass index, CA125 level, largest tumor diameter, FIGO stage, history of abdominal surgery, and American Society of Anesthesiologists grade, the rate of progression-free survival at 5 years was similar between the laparoscopy group (87.1%, 95%CI 79.3-95.7%) and the laparotomy group (90.9%, 95%CI 84.7-97.6%, p = .524), as was the rate of overall survival at 5 years (93.9%, 95%CI 88.0-100.0% vs 94.7%, 95%CI 89.8-99.9%, p = .900). Regardless of whether patients were matched, the two groups showed similar rates of recurrence of 9-11% during follow-up lasting a median of 54.9 months.Rates of recurrence and survival may be similar between laparoscopy or laparotomy to treat stage I epithelial ovarian cancer. Since laparoscopy is associated with less bleeding and faster recovery, it may be a safe, effective alternative to laparotomy for appropriate patients.Copyright © 2024. Published by Elsevier Inc.