昼夜节律紊乱与前列腺癌发病率增加密切相关。将昼夜节律纳入前列腺癌发病机制的研究中，可以更全面地了解癌症的病因，并为精准治疗提供新的选择。因此，本文全面总结了前列腺癌的流行病学，阐述了昼夜节律紊乱与前列腺癌风险之间的矛盾关系，阐明了昼夜节律调节因子与前列腺癌发病的关系。重要的是，本文还重点讨论了昼夜节律与雄激素受体信号通路之间的相关性，以及时间疗法在前列腺癌中的适用性。这可能对增强前列腺癌的临床治疗具有重要意义。版权所有 © 2024 Xia、Zhan、Wang 和 Wang。

Circadian rhythm disruption is closely related to increased incidence of prostate cancer. Incorporating circadian rhythms into the study of prostate cancer pathogenesis can provide a more comprehensive understanding of the causes of cancer and offer new options for precise treatment. Therefore, this article comprehensively summarizes the epidemiology of prostate cancer, expounds the contradictory relationship between circadian rhythm disorders and prostate cancer risk, and elucidates the relationship between circadian rhythm regulators and the incidence of prostate cancer. Importantly, this article also focuses on the correlation between circadian rhythms and androgen receptor signaling pathways, as well as the applicability of time therapy in prostate cancer. This may prove significant in enhancing the clinical treatment of prostate cancer.Copyright © 2024 Xia, Zhan, Wang and Wang.