评估Sysmex DI-60集成片制备系统对血液学差异分析周转时间及患者护理的影响：大型退伍军人事务医院的实际应用经验
Evaluating the Sysmex DI-60 Integrated Slide Processing System's impact on hematology differential turnaround times and patient care: Real-world implementation experience in a large Veterans Affairs hospital
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影响因子:1.9
分区:医学4区 / 病理学3区
发表日期:2024 Jul 19
作者:
Cory R Lundgren
DOI:
10.1093/ajcp/aqae084
摘要
本质量改进研究在密苏里州堪萨斯城的堪萨斯城退伍军人医疗中心进行，探讨了Sysmex DI-60集成片制备系统在日常实践中整合后对血液学检测周转时间的改善能力。研究还涉及与周转时间变化相关的潜在患者护理因素。分析了2022年5月至2023年2月期间的手动和Sysmex DI-60患者数据三个月。采用双尾非配对t检验和百分比变化分析白细胞（WBC）范围、周转时间、工作时间及研究月份。进一步对这些类别的标本数量进行了双尾两样本比例检验。结果显示，该系统在总体和各种WBC范围以及工作班次中，均显著缩短了周转时间，且差异具有统计学意义。特别是在WBC浓度低于2.0×10^3/µL及在参考范围内的浓度水平，改善最为显著。此外，夜班外的时间段也表现出明显的周转时间改善。Sysmex DI-60系统大幅缩短了差异分析的周转时间，潜在地通过提供快速结果改善患者护理。减少周转时间可能加快急诊科的入院及出院流程，并提升肿瘤科患者的护理效率。此外，对于Sysmex分析仪出现假阳性标志的患者，快速结果也有助于临床决策的制定。© 作者版权所有，2024年。由牛津大学出版社代表美国临床病理学会出版。所有权利保留。如需商业再用，请联系reprints@oup.com获取再版和翻译权利。其他权限可通过我们网站上的Permissions链接，使用RightsLink服务获得——详情请联系journals.permissions@oup.com。
Abstract
This quality improvement study conducted at the Kansas City VA Medical Center in Kansas City, Missouri, investigated the Sysmex DI-60 Integrated Slide Processing System's ability to improve hematology turnaround times when integrated into daily practices. It further addressed potential patient care factors associated with changes in turnaround times.Three months of manual and Sysmex DI-60 patient data were examined between May 2022 and February 2023. White blood cell (WBC) ranges, turnaround times, working hours, and study months were analyzed using 2-tailed unpaired t testing and percentage change. The number of specimens in these categories was further analyzed using 2-tailed, 2-sample proportion testing.This quality improvement study indicated that the Sysmex DI-60 system produced a statisitcally significant reduction in turnaround times overall and for various ranges of WBCs plus work shifts. The most statistically significant improvement in turnaround times occurred for WBC concentrations less than 2.0 × 103/µL and concentrations within the reference range. In addition, the off shifts experienced a notable improvement in turnaround times.The Sysmex DI-60 system substantially decreases turnaround times for differentials, thus potentially benefiting patient care by providing prompt results. It is possible that reducing turnaround times could expedite emergency department admissions and discharges as well as enhance care for the oncology department's patients. It could also lead to more timely results for patients with false-positive flags by the Sysmex analyzer, which may also help with clinician decision-making.© The Author(s) 2024. Published by Oxford University Press on behalf of American Society for Clinical Pathology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.