感觉缺陷会影响对环境的认识和信息处理，导致功能障碍，从而可能产生严重后果。味觉和/或嗅觉的恶化与营养摄入受损和整体生活质量 (QoL) 下降有关。最近的数据表明，这些感觉的丧失也与认知能力下降和整体癌症治疗预后较差有关。癌症治疗通常与感觉恶化有关。我们根据新发现回顾了这些与味觉和嗅觉的关联，并讨论了味觉和嗅觉功能的潜在预防和治疗方式。© 2024 John Wiley

Sensory deficits affect awareness of the environment and information processing, leading to dysfunction that may have significant consequences. Deterioration of taste and/or smell sensation has been linked to impaired nutritional intake, and overall decreased quality of life (QoL). Recent data suggest that loss of these senses is also associated with cognitive decline and worse overall cancer treatment prognosis. Cancer therapies have commonly been associated with sensory deterioration. We review these associations with taste and smell in light of new findings and discuss potential prophylactic and therapeutic modalities for taste and smell function.© 2024 John Wiley & Sons Ltd.