癌症仍然是全球主要的健康挑战，尽管有可用的治疗方法，但其预后仍然不佳。最近，研究人员将注意力转向用于癌症药物输送的智能纳米纤维。这些纳米纤维在靶向和控制药物释放方面表现出卓越的能力。它们的固有特性，例如高表面积与体积比，使它们成为药物输送应用的有吸引力的候选者。智能纳米纤维可以响应特定刺激（包括 pH、温度、磁场和光）释放药物。这一独特的功能不仅减少了副作用，还提高了药物输送系统的整体效率。静电纺丝是一种广泛使用的方法，可以精确制造智能纳米纤维。其优点包括效率高、用户友好以及能够控制各种制造参数。在这篇综述中，我们探讨了生产用于癌症治疗的智能电纺纳米纤维的最新进展。此外，我们还讨论了制造这些纳米纤维所使用的材料以及静电纺丝过程中涉及的关键参数。© 2024 作者。

Cancer remains a major global health challenge, and despite available treatments, its prognosis remains poor. Recently, researchers have turned their attention to intelligent nanofibers for cancer drug delivery. These nanofibers exhibit remarkable capabilities in targeted and controlled drug release. Their inherent characteristics, such as a high surface area-to-volume ratio, make them attractive candidates for drug delivery applications. Smart nanofibers can release drugs in response to specific stimuli, including pH, temperature, magnetic fields, and light. This unique feature not only reduces side effects but also enhances the overall efficiency of drug delivery systems. Electrospinning, a widely used method, allows the precision fabrication of smart nanofibers. Its advantages include high efficiency, user-friendliness, and the ability to control various manufacturing parameters. In this review, we explore the latest developments in producing smart electrospun nanofibers for cancer treatment. Additionally, we discuss the materials used in manufacturing these nanofibers and the critical parameters involved in the electrospinning process.© 2024 The Authors.