CMR 参数映射在常见良性儿科心脏肿瘤组织表征中的附加价值。
Additional value of CMR parametric mapping in tissue characterization of common benign pediatric cardiac tumors.
发表日期:2024 Jul 25
作者:
Paolo Ciliberti, Veronica Bordonaro, Davide Curione, Alessio Perazzolo, Paolo Ciancarella, Teresa Santangelo, Carmela Napolitano, Luigi Natale, Lorenzo Galletti, Aurelio Secinaro
来源:
European Heart Journal-Cardiovascular Imaging
摘要:
心脏磁共振 (CMR) 参数映射在心脏肿瘤中的研究尚未充分。旨在评估映射序列对儿科肿瘤特征的贡献。2017 年 6 月至 2023 年 11 月在 Bambino Gesù 儿童医院转诊的所有因心脏肿瘤而接受 CMR 的儿科患者与映射序列,被包括在内。根据不同序列上的信号特征进行肿瘤类型的诊断。评估了每个亚型的质量参数图和观察者间的变异性。招募了 16 名患者。 CMR 的平均年龄为 7 ± 5 岁。 “传统”肿块型评估诊断出血管瘤(A 组)3 名患者(19%)、纤维瘤(B 组)4 名患者(25%)、横纹肌瘤(C 组)6 名患者(37%)和脂肪瘤( D组)有3名患者(19%)。方差分析显示四个亚组之间的质量天然 T1 和质量细胞外体积 (ECV) 值存在显着差异(两次比较 p<0.001)。 A 组的平均原始 T1 和 ECV 值分别为 1465 ± 158 毫秒和 54 ± 4%,B 组为 860 ± 118 毫秒和 93 ± 4%,C 组为 1007 ± 57 毫秒和 23 ± 5%,以及 215 D 组为 ± 13 毫秒和 0 ± 0%。质量图谱分析在儿童中是可行且可重复的。 ECV 值提供最准确的区分。横纹肌瘤中的质量 ECV 始终与正常心肌相似,纤维瘤中的质量 ECV 极高(接近 100%),脂肪瘤中为零,并且与血管瘤中的血池 ECV (1-Hct) 相匹配。© 作者 2024 年。由牛津出版大学出版社代表欧洲心脏病学会。
Cardiac Magnetic Resonance (CMR) parametric mapping is underexplored in cardiac tumors.To evaluate the contribution of mapping sequences on the characterization of pediatric tumors.All pediatric patients referred for cardiac tumors at Bambino Gesù Children's Hospital from June 2017 to November 2023, who underwent CMR with mapping sequences, were included. The diagnosis of tumor type was performed according to signal characteristics on different sequences. Mass parametric mapping for each subtype and interobserver variability was assessed.Sixteen patients were enrolled. The mean age at CMR was 7 ± 5 years. "Traditional" mass-type assessment diagnosed hemangioma (Group A) in 3 patients (19%), fibroma (Group B) in 4 patients (25%), rhabdomyoma (Group C) in 6 patients (37%), and lipoma (Group D) in 3 patients (19%). The ANOVA analysis revealed significant differences in mass native T1 and mass extracellular volume (ECV) values among the four subgroups (p<0.001 for both comparisons). The mean native T1 and ECV values were respectively 1465 ± 158 msec and 54 ± 4% for Group A, 860 ± 118 msec and 93 ± 4% for Group B, 1007 ± 57 msec and 23 ± 5% for Group C, and 215 ± 13 msec and 0 ± 0% for Group D.Mass mapping analysis is feasible and reproducible in children. ECV values provide the most accurate differentiation. Mass ECV consistently resembles normal myocardium in rhabdomyoma, is extremely high (approaching 100%) in fibroma, equals to zero in lipoma, and matches blood pool ECV (1-Hct) in hemangioma.© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.