早期发现对于提高肺癌生存率至关重要。诊断延迟可能会对疾病的预后产生负面影响。本研究旨在分析肺癌患者的诊断延迟，并描述延迟与生存之间是否存在关联。使用的数据来源是西班牙肺癌组的胸部肿瘤登记处。该分析仅限于肺癌病例，其中包含按症状首次就诊日期和诊断日期的信息。延迟计算为两个日期之间的天数。进行了描述性分析，并以延迟作为因变量进行序数逻辑回归拟合。进行了 Kaplan-Meier 生存分析和 Cox 回归。纳入了 22,755 例肺癌病例。从不吸烟者延迟时间较长的可能性是吸烟者的 1.16 倍（95%CI：1.06-1.27）。与 III-IV 期相比，0-I-II 期病例的较长时间延误风险高出 3.09（95%CI：2.88-3.32）。总体而言，诊断后 5 年生存率为 23.64%（95%CI：22.88-24.41）。在最短延迟的患者中，5 年生存率为 17.67% (95%CI: 16.31-19.07)，在极端延迟的患者中，5 年生存率为 32.98% (95%CI: 31.28-34.69) (p<0.001)。与极端延迟相比，最短延迟的患者（HR 1.36，CI95%：1.30-1.43）调整后的死亡风险较高。西班牙肺癌患者的诊断延迟时间较短，表明诊断过程相对较快。极端延迟似乎与较高的生存率相关，可能归因于肿瘤生长缓慢、诊断​​较早或基本上是这种疾病的自然史。版权所有 © 2024 作者。由 Elsevier España 出版，S.L.U.版权所有。

Early detection is crucial to improve lung cancer survival rates. Delays in diagnosis might negatively impact the prognosis of the disease. This study aims to analyze the diagnostic delay in lung cancer patients and describe if there is an association between delay and survival.The data source used was the Thoracic Tumor Registry of the Spanish Lung Cancer Group. This analysis was restricted to lung cancer cases with information on the first date of consultation by symptoms and date of diagnosis. The delay was calculated as the number of days between the two dates. A descriptive analysis was performed, and ordinal logistic regressions were fitted with delay as the dependent variable. Kaplan-Meier survival analysis and Cox regression were performed.22,755 lung cancer cases were included. Never smokers were 1.16 (95%CI: 1.06-1.27) times more likely to register longer delay than smokers. Stage 0-I-II cases had a 3.09 (95%CI: 2.88-3.32) higher risk of longer delay compared to III-IV stages. Overall, 5-year survival rate after diagnosis was 23.64% (95%CI: 22.88-24.41). In those categorized as having the shortest delay 5-year survival was 17.67% (95%CI: 16.31-19.07) and in the extreme delay it was 32.98% (95%CI: 31.28-34.69) (p<0.001). Adjusted mortality risk was higher in those with the shortest delay (HR 1.36, CI95%: 1.30-1.43) in comparison with the extreme delay.Diagnostic delay is short among Spanish lung cancer patients, indicating a relatively quick diagnostic process. Extreme delays appear to be associated with higher survival rates, possibly attributed to slow-growing tumors, earlier stage at diagnosis or basically the natural history of this disease.Copyright © 2024 The Author(s). Published by Elsevier España, S.L.U. All rights reserved.