研究动态
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乳头瘤病毒 mRNA 的翻译控制成为人们关注的焦点。

Translational control of papillomavirus mRNAs in the spotlight.

发表日期:2024 Jul 27
作者: Alejandra García, Giovanna Maldonado, Greco Hernández
来源: TRENDS IN CELL BIOLOGY

摘要:

大多数宫颈癌病例都是由高危人乳头瘤病毒 (HPV) 引起的,这种疾病在全球范围内的影响越来越大。最近的研究表明,病毒癌蛋白的合成强烈受到翻译控制。因此,针对蛋白质合成机制可能会开辟新的途径来开发旨在提高患者生存率的创新疗法。版权所有 © 2024 Elsevier Ltd。保留所有权利。
High-risk human papillomaviruses (HPVs) cause most cases of cervical cancer, a disease with an increasing impact worldwide. Recent studies have shown that the synthesis of viral oncoproteins is strongly subject to translational control. Thus, targeting the protein synthesis machinery might open novel avenues to develop innovative therapies aiming to improve patients' survival.Copyright © 2024 Elsevier Ltd. All rights reserved.