本研究旨在描述我们在机器人辅助胸腔手术 (RATS) 方面的大量单中心经验，以评估该技术的短期结果和可行性、肿瘤学结果的充分性以及学习曲线。我们回顾性分析了来自 1000 名连续患者的数据2007 年 5 月至 2023 年 5 月期间，使用 RATS 方法对原发性肺癌进行了肺叶切除术和系统性淋巴结切除术。997 名患者 (99.7%) 接受了肺叶切除术，而 3 名患者 (0.03%) 接受了双肺叶切除术。开放手术的转化率为 3.7%。 213 名患者 (21.3%) 发生轻微并发症，29 名患者 (2.9%) 发生严重并发症。 30 天和 90 天的手术死亡率分别为 0% 和 0.1%。切除的 N1 N2 站中位数为 5 个（范围 0-9），切除的 N1 N2 淋巴结中位数为 17 个（范围 0-55）。仅对非小细胞肺癌患者亚组 (n = 895) 评估肿瘤学结果。 147 名患者 (17.3%) 的病理淋巴结从 cN0 升级为 pN1/pN2：9% 从 cN0 升级到 pN1，7.1% 从 cN0 升级到 pN2。中位随访时间为 3.9，I 期的 5 年 OS 和 DFS 分别为 89.3% 和 83.6%，II 期为 74% 和 66.5%，IIIA 期为 61% 和 36.4%。更好的视力和出色的仪器机器人手术系统的可操作性在早期、足够的肿瘤学结果方面取得了优异的结果，与开放式手术文献数据相当，并且学习曲线可接受。使用 RATS 方法对 1000 名连续接受原发性肺癌肺叶切除术和系统性淋巴结切除术的患者进行了分析旨在描述我们的大批量单中心经验，并评估该技术的短期结果和可行性、肿瘤学结果的充分性和学习曲线。版权所有 © 2024 Elsevier B.V. 保留所有权利。

This study aimed at describing our high-volume single center experience in robotic-assisted thoracic surgery (RATS) to evaluate short outcome and feasibility of the technique, the adequacy of oncological results, and the learning curve.We retrospectively analyzed data from 1000 consecutive patients who underwent lobectomy and systematic lymphadenectomy for primary lung cancer using RATS approach between May 2007 and May 2023.Nine-hundred ninety-seven patients (99.7 %) underwent lobectomy, whereas 3 (0.03 %) patients bilobectomy. Conversion rate to open surgery was 3.7 %. Minor complications occurred in 213 (21.3 %) patients, major complications in 29 patients (2.9 %). The 30-day and 90-day operative mortality was 0 % and 0.1 %, respectively. The median number of N1 + N2 stations resected was 5 (range 0-9), with a median number of 17 of N1 + N2 lymph nodes resected (range 0-55). The oncological outcome was evaluated only on the subgroup of patients (n = 895) with non-small cell lung cancer. Pathological lymph node upstaging from cN0 to pN1/pN2 was evident in 147 patients (17.3 %): 9 % from cN0 to pN1 and 7.1 % from cN0 to pN2. With a median follow-up of 3.9, 5-year OS and DFS were respectively 89.3 % and 83.6 % for stage I, 74 % and 66.5 % for stage II, and 61 % and 36.4 % for stage IIIA.Better vision and excellent instrument maneuverability of the robotic surgical system allowed excellent results in terms of early, adequate oncological outcome comparable to open surgery literature data, and acceptable learning curve.1000 consecutive patients who underwent lobectomy and systematic lymphadenectomy for primary lung cancer using RATS approach have been analyzed with the aim to describe our high-volume single center experience, and to evaluate short outcome and feasibility of the technique, the adequacy of oncological results, and the learning curve.Copyright © 2024 Elsevier B.V. All rights reserved.