非典型梭形细胞/多形性脂肪瘤被归类为良性脂肪瘤，但各种 MRI 结果对准确的诊断提出了挑战。在我们的病例中，MRI 和 PET/CT 扫描均表明非典型脂肪瘤/高分化脂肪肉瘤或去分化脂肪肉瘤的可能性。针刺活检提示良性至低度恶性肿瘤；因此，我们选择了广泛切除。通过组织病理学分析，包括免疫组织化学和荧光原位杂交，最终诊断为非典型梭形细胞/多形性脂肪瘤。由于仅通过成像实现准确诊断具有挑战性，因此组织病理学仍然至关重要。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。

Atypical spindle cell/pleomorphic lipomatous tumor is categorized as a benign lipomatous tumor, but various MRI findings pose accurate diagnostic challenges. In our case, both MRI and PET/CT scans indicated the possibility of atypical lipomatous tumor/well-differentiated liposarcoma or dedifferentiated liposarcoma. Needle biopsy suggested benign to low-grade malignancy; hence, we opted for the wide resection. The final diagnosis of atypical spindle cell/pleomorphic lipomatous tumor was confirmed through histopathology analysis, including immunohistochemistry and fluorescence in situ hybridization. Since achieving an accurate diagnosis solely through imaging can be challenging, histopathology remains essential.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.