无症状绝经后妇女子宫内膜息肉的患病率尚不清楚。关于如何治疗该人群中的子宫内膜息肉以及这些息肉是否确实引起临床关注，尚无明确的临床共识。 估计无症状（无出血）绝经后妇女中子宫内膜息肉的患病率，并评估与其相关的危险因素这项横断面研究评估了因子宫阴道脱垂而接受子宫切除术的无症状绝经后妇女中子宫内膜息肉的患病率。如果患者因其他适应症（包括绝经后出血）而接受子宫切除术，则被排除在外。图表审查包括 2009 年至 2018 年在华盛顿州单一地点接受护理的符合条件的患者。主要结果是病理学上是否存在子宫内膜息肉。随后使用单变量分析和多变量回归评估与息肉患病率相关的危险因素。在确定的 317 名符合条件的女性中，有 106 名女性 (33.4%) 发现子宫内膜息肉。息肉平均大小和子宫内膜厚度分别为13±10mm和1.4±1.5mm。大多数病例（78%）有孤立性息肉。癌前及恶性病变2例（1.89%）；一名患有子宫内膜癌，一名患有子宫内膜上皮内瘤变。患有和不患有子宫内膜息肉的患者的基线临床和人口统计学特征相似，包括是否存在子宫肌瘤、子宫内膜异位症和子宫腺肌病。多变量逻辑回归显示，息肉的存在与高体重指数（OR 1.06，95%-CI 1.01-1.12，p 值 0.02）和绝经期激素治疗的使用（OR 1.67，95%-CI 1.02 - 2.72）独立相关。 ，p 值 0.04)。因子宫阴道脱垂而接受子宫切除术的无症状绝经后妇女表现出子宫内膜息肉的高患病率。那些使用更年期激素治疗和高体重指数的人患子宫内膜息肉的风险较高。虽然恶性风险似乎很低，但需要进行更多调查才能真正量化终生风险。目前，对于偶然发现的无症状息肉，期待治疗可能是一种合理的方法。版权所有 © 2024 Elsevier Inc. 保留所有权利。

The prevalence of endometrial polyps among asymptomatic, postmenopausal women is not well defined. There is no clear clinical consensus on how to manage endometrial polyps in this population and whether these polyps truly are cause for clinical concern.To estimate the prevalence of endometrial polyps among asymptomatic (without bleeding), postmenopausal women, and evaluate risk factors associated with their presence.This cross-sectional study assessed the prevalence of endometrial polyps among asymptomatic, postmenopausal women undergoing hysterectomy for uterovaginal prolapse. Patients were excluded if undergoing hysterectomy for other indications including postmenopausal bleeding. Chart review included eligible patients who received care at a single-site in Washington state from 2009 to 2018. The primary outcome was presence of endometrial polyps on pathology. Risk factors associated with polyp prevalence were subsequently assessed using univariate analysis and multivariate regression.Of the 317 eligible women identified, endometrial polyps were identified in 106 women (33.4%). The average polyp size and endometrial thickness was 13 +/- 10mm and 1.4 +/- 1.5mm. Most cases, 78%, had solitary polyps. Premalignant and malignant lesions were found in 2 cases (1.89%); one had endometrial carcinoma and one had endometrial intraepithelial neoplasia. Baseline clinical and demographic characteristics were similar between patients with and without endometrial polyps, including the presence of fibroids, endometriosis and adenomyosis. Multivariate logistic regression showed that presence of polyps was independently associated with high body mass index (OR 1.06, 95%-CI 1.01-1.12, p-value 0.02) and use of menopausal hormone therapy (OR 1.67, 95%-CI 1.02 - 2.72, p-value 0.04).Asymptomatic postmenopausal women undergoing hysterectomy for uterovaginal prolapse exhibit a high prevalence of endometrial polyps. Those with use of menopausal hormone therapy and high body mass index are at a higher risk of developing endometrial polyps. While the malignant risk seems to be low, more investigation is warranted to truly quantify the lifetime risk. For now, expectant management may be a reasonable approach for incidentally found, asymptomatic polyps.Copyright © 2024 Elsevier Inc. All rights reserved.