大 B 细胞淋巴瘤的中枢神经系统预防：英国血液学会良好实践论文。
Central nervous system prophylaxis in large B-cell lymphoma: A British Society for Haematology Good Practice Paper.
发表日期：2024 Aug 11
作者：
Matthew R Wilson, Kate Cwynarski, Toby A Eyre, Jeffery Smith, Sridhar Chaganti, Christopher P Fox, Pamela McKay
来源：
BRITISH JOURNAL OF HAEMATOLOGY
摘要：
本良好实践文件为有中枢神经系统复发风险的大 B 细胞淋巴瘤患者的基线调查、风险分层和预防性干预措施的使用提供了建议。详细讨论了质疑高剂量甲氨蝶呤在这种临床情况中的作用的最新证据。© 2024 英国血液学会和 John Wiley
This Good Practice Paper provides recommendations for the baseline investigation, risk stratification and use of prophylactic interventions for patients with large B-cell lymphoma at risk of central nervous system relapse. Recent evidence which has questioned the role of high-dose methotrexate in this clinical scenario is discussed in detail.© 2024 British Society for Haematology and John Wiley & Sons Ltd.